Page 88 - Read Online
P. 88

Page 16 of 20                                 Ho et al. J Cancer Metastasis Treat 2019;5:70  I  http://dx.doi.org/10.20517/2394-4722.2019.25

               38.  Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature 2011;469:323-35.
               39.  Deretic V, Saitoh T, Akira S. Autophagy in infection, inflammation and immunity. Nat Rev Immunol 2013;13:722-37.
               40.  Wu TT, Li WM, Yao YM. Interactions between autophagy and inhibitory cytokines. Int J Biol Sci 2016;12:884-97.
               41.  Djavaheri-Mergny M, Giuriato S, Tschan MP, Humbert M. Therapeutic modulation of autophagy in leukaemia and lymphoma. Cells
                   2019;8:E103.
               42.  Mortensen M, Watson AS, Simon AK. Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell
                   function and dysregulated myeloid proliferation. Autophagy 2011;7:1069-70.
               43.  Warr MR, Binnewies M, Flach J, Reynaud D, Garg T, et al. FOXO3A directs a protective autophagy program in haematopoietic stem
                   cells. Nature 2013;494:323-7.
               44.  Ho TT, Warr MR, Adelman ER, Lansinger OM, Flach J, et al. Autophagy maintains the metabolism and function of young and old
                   stem cells. Nature 2017;543:205.
               45.  Ianniciello A, Rattigan KM, Helgason GV. The Ins and Outs of autophagy and metabolism in hematopoietic and leukemic stem cells:
                   food for thought. Front Cell Dev Biol 2018;6:120.
               46.  Mortensen M, Soilleux EJ, Djordjevic G, Tripp R, Lutteropp M, et al. The autophagy protein Atg7 is essential for hematopoietic stem
                   cell maintenance. J Exp Med 2011;208:455-67.
               47.  Ho Zhi Guang M, Kavanagh EL, Dunne LP, Dowling P, Zhang L, et al. Targeting proteotoxic stress in cancer: a review of the role that
                   protein quality control pathways play in oncogenesis. Cancers 2019;11:66.
               48.  Nutt SL, Taubenheim N, Hasbold J, Corcoran LM, Hodgkin PD. The genetic network controlling plasma cell differentiation. Semin
                   Immunol 2011;23:341-9.
               49.  Reimold AM, Iwakoshi NN, Manis J, Vallabhajosyula P, Szomolanyi-Tsuda E, et al. Plasma cell differentiation requires the
                   transcription factor XBP-1. Nature 2001;412:300-7.
               50.  Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, et al. XBP1, downstream of Blimp-1, expands the secretory apparatus
                   and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004;21:81-93.
               51.  Tellier J, Shi W, Minnich M, Liao Y, Crawford S, et al. Blimp-1 controls plasma cell function through the regulation of
                   immunoglobulin secretion and the unfolded protein response. Nat Immunol 2016;17:323-30.
               52.  Pengo N, Scolari M, Oliva L, Milan E, Mainoldi F, et al. Plasma cells require autophagy for sustainable immunoglobulin production.
                   Nat Immunol 2013;14:298-305.
               53.  Halliley JL, Tipton CM, Liesveld J, Rosenberg AF, Darce J, et al. Long-lived plasma cells are contained within the CD19(-)CD38(hi)
                   CD138(+) subset in human bone marrow. Immunity 2015;43:132-45.
               54.  Pengo N, Cenci S. Chapter 6 - autophagy in plasma cells. Autophagy: cancer, other pathologies, inflammation, immunity, infection,
                   and aging. Academic Press; 2017. pp. 175-86.
               55.  Cenci S, Oliva L, Cerruti F, Milan E, Bianchi G, et al. Pivotal advance: protein synthesis modulates responsiveness of differentiating
                   and malignant plasma cells to proteasome inhibitors. J Leukoc Biol 2012;92:921-31.
               56.  Leung-Hagesteijn C, Erdmann N, Cheung G, Keats JJ, Stewart AK, et al. Xbp1s-negative tumor B cells and pre-plasmablasts mediate
                   therapeutic proteasome inhibitor resistance in multiple myeloma. Cancer Cell 2013;24:289-304.
               57.  Meister S, Schubert U, Neubert K, Herrmann K, Burger R, et al. Extensive immunoglobulin production sensitizes myeloma cells for
                   proteasome inhibition. Cancer Res 2007;67:1783-92.
               58.  Cenci S. The proteasome in terminal plasma cell differentiation. Semin Hematol 2012;49:215-22.
               59.  Ling SC, Lau EK, Al-Shabeeb A, Nikolic A, Catalano A, et al. Response of myeloma to the proteasome inhibitor bortezomib is
                   correlated with the unfolded protein response regulator XBP-1. Haematologica 2012;97:64-72.
               60.  Milan E, Fabbri M, Cenci S. Autophagy in plasma cell ontogeny and malignancy. J Clin Immunol 2016;36 Suppl 1:18-24.
               61.  Snyder H, Mensah K, Theisler C, Lee J, Matouschek A, et al. Aggregated and monomeric alpha-synuclein bind to the S6’ proteasomal
                   protein and inhibit proteasomal function. J Biol Chem 2003;278:11753-9.
               62.  Yao TP. The role of ubiquitin in autophagy-dependent protein aggregate processing. Genes Cancer 2010;1:779-86.
               63.  Le T, Bhushan V, Sochat M. First aid for the USMLE Step 1; 2019. ISBN: 978-1-26-014367-6
               64.  Milan E, Perini T, Resnati M, Orfanelli U, Oliva L, et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis
                   and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy 2015;11:1161-78.
               65.  Hoang B, Benavides A, Shi Y, Frost P, Lichtenstein A. Effect of autophagy on multiple myeloma cell viability. Mol Cancer Ther
                   2009;8:1974-84.
               66.  Caro LH, Plomp PJ, Wolvetang EJ, Kerkhof C, Meijer AJ. 3-Methyladenine, an inhibitor of autophagy, has multiple effects on
                   metabolism. Eur J Biochem 1988;175:325-9.
               67.  Lamy L, Ngo VN, Emre NC, Shaffer AL 3rd, Yang Y, et al. Control of autophagic cell death by caspase-10 in multiple myeloma.
                   Cancer Cell 2013;23:435-49.
               68.  Yu L, Alva A, Su H, Dutt P, Freundt E, et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science
                   2004;304:1500-2.
               69.  Grek CL, Tew KD. Redox metabolism and malignancy. Curr Opin Pharmacol 2010;10:362-8.
               70.  Kryston TB, Georgiev AB, Pissis P, Georgakilas AG. Role of oxidative stress and DNA damage in human carcinogenesis. Mutat Res
                   2011;711:193-201.
               71.  Wu W, Tian W, Hu Z, Chen G, Huang L, et al. ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate
                   mitophagy. EMBO Rep 2014;15:566-75.
   83   84   85   86   87   88   89   90   91   92   93