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Page 4 of 16                                                 Silk et al. Hepatoma Res 2020;6:73  I  http://dx.doi.org/10.20517/2394-5079.2020.61

                A                           B                              C













                D                                                          F



                                            E






















               Figure 1. Clinical spectrum of HFRS of grade 1 (A,D) grade 2 (B,E) and grade 3(C,F). Used with permission from Lipworth et al. [13] ,
               Copyright © 2009 Karger Publishers, Basel, Switzerland. HFRS: hand foot reaction syndrome


































               Figure 2. Example of rash on the trunk with TKI treatment. Used with permission under the Creative Commons Attribution License. (http://
                                          [31]
               creativecommons.org/licenses/by/2.0) . TKI: tyrosine kinase inhibitor
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