Page 798 - Read Online

Calabrò et al. Hepatoma Res 2020;6:69 Hepatoma Research
DOI: 10.20517/2394-5079.2020.63

Review Open Access

Beneficial effects of coffee in non-alcoholic fatty
liver disease: a narrative review

Alessio Calabrò , Anna Caterina Procopio , Francesco Primerano , Tiziana Larussa , Francesco Luzza ,
2
3
2
2
1
Laura Di Renzo , Antonino De Lorenzo , Paola Gualtieri , Ludovico Abenavoli 2
4
4
4
1 Indipendent Nutritionist, Viale dei Bizantini 25, Catanzaro 88100, Italy.
2 Department of Health Sciences, University “Magna Graecia” of Catanzaro, Viale Europa, Catanzaro 88100, Italy.
3 Indipendent Biomedical Engineer, Viale degli Aurunci 9, 88060 Montepaone, Catanzaro 88100, Italy.
4 Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Rome 00133, Italy.
Correspondence to: Prof. Ludovico Abenavoli, Department of Health Sciences, University “Magna Graecia” of Catanzaro, Viale
Europa, Catanzaro 88100, Italy. E-mail: l.abenavoli@unicz.it
How to cite this article: Calabrò A, Procopio AC, Primerano F, Larussa T, Luzza F, Di Renzo L, De Lorenzo A, Gualtieri P, Abenavoli
L. Beneficial effects of coffee in non-alcoholic fatty liver disease: a narrative review. Hepatoma Res 2020;6:69.
http://dx.doi.org/10.20517/2394-5079.2020.63
Received: 25 Jun 2020 First Decision: 18 Aug 2020 Revised: 3 Sep 2020 Accepted: 8 Sep 2020 Published: 12 Oct 2020

Academic Editor: Guang-Wen Cao Copy Editor: Cai-Hong Wang Production Editor: Jing Yu
Received: First Decision: Revised: Accepted: Published:

Science Editor: Copy Editor: Production Editor: Jing Yu Abstract
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases and is related to unhealthy
lifestyle habits, characterized by a diet rich in sugars and fats leading to excessive calorie intake, and lack of
exercise. In recent years, there is a growing incidence of this pathology, raising the attention of hepatologists,
endocrinologists, diabetologists, and nutritionists. In this context, the alimentary regimen adopted by patients
with NAFLD has become an increasingly scrutinised parameter. Diet is now considered a crucial factor in the
treatment of NAFLD since it has been observed that some functional foods play a beneficial role. These include
coffeewhose health effects have already been amply demonstrated. Here we describe the beneficial effects of
coffee consumption reported in the NAFLD literature.

Keywords: Caffeine, steatosis, functional food, liver disease, antioxidant, chlorogenic-acid

INTRODUCTION
Non-alcoholic fatty liver disease (NAFLD) is a common liver pathology characterized by fat accumulation
in the liver, following a sequence of steatosis, possible evolution in fibrosis, Non-alcoholic steatohepatitis

© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use,
sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long
as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license,
and indicate if changes were made.

www.hrjournal.net