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Chen et al. Hepatoma Res 2018;4:4 I http://dx.doi.org/10.20517/2394-5079.2017.50 Page 9 of 10

aflatoxin B1. Tumor 1981;1:1-5.
6. Li WG, Xie JR, Yu SY, Chu YJ, Gong XL. Relationship between geographic distribution of primary liver cancer and selenium level in
Qidong county. Trace Elements 1986;(3):58-61.
7. Liu PL, Su DL, Yu SZ, Li WG. HBV seroepidemiological study in population with different drinking water sources in Qidong county.
Acta Acad Med Prim Shanghai 1985;12:427-34.
8. Chen JG. Liver cancer endemic trend between 1972 and 1981 in Qidong county. J Med Res 1983;(12):13-5.
9. Yang L, Parkin DM, Whelan S, Zhang S, Chen Y, Lu F, Li L. Statistics on cancer in China: cancer registration in 2002. Eur J Cancer
Prev 2005;14:329-35.
10. Sun GJ, He X, Qian GS, Pu YP, Jin XP, Wang JS. Detecting urine aflatoxin metabolism by high performance liquid chromatography. J
Health Toxicol 2000;14:250-2.
11. Sun GJ, He X, Qian GS, Pu YP, Jin XP, Wang JS. Detection of aflatoxin-ablumin adducts in human serum and its application. Wei Sheng
Yan Jiu 2001;30:185-7. (in Chinese)
12. Wu YQ, Wan SG, Lu PX, Wang JS, Kuang SY, Wang JB, Fang X, Wu Y, Zhang QN, Qu Q, Kensler T, Groopman J, Qian GS. Genotype
of GSTT1 and GSTM1 among population in Qidong liver cancer high incidence field. Natl Med J China 1999;79:517-8.
13. Wu YQ, Lu PX, Wang JS, Wang JB, Wan SG, Kensler TW, Groopman JD, Qian GS. Correlation between the genetic polymorphism of
EPHX and susceptibility to hepatocellular carcinoma. Tumor 2003;23:287-9.
14. Xu L, Wu YQ, Jin Y, Yu YM, Qian GS. A case-control study on polymorphism of DNA repair gene XPD and susceptibility to
hepatocellular carcinoma. Tumor 2004;24:526-9.
15. Qian GS, Kuang SY, He X, Groopman JD, Jackson PE. Sensitivity of electrospray ionization mass spectrometry detection of codon 249
mutations in the p53 gene compared with RFLP. Cancer Epidemiol Biomarkers Prev 2002;11:1126-9.
16. Kuang SY, Jackson PE, Wang JB, Lu PX, Muñoz A, Qian GS, Kensler TW, Groopman JD. Specific mutations of hepatitis B virus in
plasma predict liver cancer development. Proc Natl Acad Sci U S A 2004;101:3575-80.
17. Guo X, Jin Y, Qian GS, Xu L, Tu H. Full-genome sequence analysis of hepatitis B virus isolated from hepatocellular carcinoma in high
incidence area Qidong. Tumor 2007;27:429-32.
18. Bai X, Zhu Y, Jin Y, Guo X, Qian G, Chen T, Zhang J, Wang J, Groopman JD, Gu J, Tu H. Temporal acquisition of sequential mutations
in the enhancer II and basal core promoter of HBV in individuals at high risk for hepatocellular carcinoma. Carcinogenesis 2011;32:63-8.
19. Guo X, Jin Y, Qian G, Tu H. Sequential accumulation of the mutations in core promoter of hepatitis B virus is associated with the
development of hepatocellular carcinoma in Qidong, China. J Hepatol 2008;49:718-25.
20. Bai X, Zhu Y, Jin Y, Cai X, Guo X, Qian G, Chen T, Zhang J, Wang J, Tu H. Correlation of the mutations in N terminal of hepatitis B
virus X protein with tumorigenesis of hepatocellular carcinoma. Tumor 2010;30:433-7.
21. Cao Z, Bai X, Guo X, Jin Y, Qian G, Tu H. High prevalence of hepatitis B virus pre-S mutation and its association with hepatocellular
carcinoma in Qidong, China. Arch Virol 2008;153:1807-12.
22. Zhu Y, Jin Y, Cai X, Bai X, Chen M, Chen T, Wang J, Qian G, Gu J, Li J, Tu H. Hepatitis B virus core protein variations differ in tumor
and adjacent nontumor tissues from patients with hepatocellular carcinoma. Intervirology 2012;55:29-35.
23. Zhu Y, Jin Y, Guo X, Bai X, Chen T, Wang J, Qian G, Groopman JD, Gu J, Li J, Tu H. Comparison study on the complete sequence of
hepatitis B virus identifies new mutations in core gene associated with hepatocellular carcinoma. Cancer Epidemiol Biomarkers Prev
2010;19:2623-30.
24. Wu Y, Gan Y, Gao F, Zhao Z, Jin Y, Zhu Y, Sun Z, Wu H, Chen T, Wang J, Sun Y, Fan C, Xiang Y, Qian G, Groopman JD, Gu J, Tu
H. Novel natural mutations in the Hepatitis B Virus reverse transcriptase domain associated with hepatocellular carcinoma. PLoS One
2014;9:1-10.
25. Gao FM, Wu Y, Zhao ZM, Jin Y, Qian GS, Chen TY, Zhang YW, Wang JB, Gan Y, Xiang YB, Tu H. The association between mutations
in the reverse transcriptase domain of hepatitis B virus polymerase gene with tumorigenesis of hepatocellular carcinoma. Tumor
2014;34:141-6.
26. Zhao ZM, Zhu Y, Wu Y, Fan CS, Chen TY, Gan Y, Tu H. Development and application of a reverse hybridization method for detection
of hepatitis B virus precore mutation associated with hepatocellular carcinoma. China Oncol 2014;24:266-72.
27. Zhao ZM, Jin Y, Gan Y, Zhu Y, Chen TY, Wang JB, Sun Y, Cao ZG, Qian GS, Tu H. Novel approach to identifying the hepatitis B virus
pre-S deletions associated with hepatocellular carcinoma. World J Gastroenterol 2014;20:13573-81.
28. Lu P, Kuang S, Wang J, Fang X, Zhang Q, Wu Y, Lu Z, Qian G. Hepatitis B virus infection and aflatoxin exposure in the development
of primary liver cancer. Natl Med J China 1998;78:340-2.
29. Lu P, Zhang Q, Huang Q, Wei Y. The HBV and HCV infection rates among various populations in high incidence area of hepatocellular
carcinoma (HCC) and their relationship with HCC. Tianjin Med J 1999;27:6-7.
30. Lu P, Wang J, Wu Y, Zhang Q, Wu Y, Wan S, Kuang S, Wang N, Qian G. Significance of prospective follow-up cohort study in diagnosis
and treatment of primary hepatic cancer among HBsAg carriers. Natl Med J China 2001;81:856-9.
31. Sun Y, Lu P, Wang J, Wu Y, Zhang Q, Chen T. A prospective study of the relationship between hepatitis B virus markers and primary
liver cancer. Tianjin Med J 2010;38:81-3.
32. Sun Y, Chen T, Lu P, Wang J, Wu Y, Zhang Q, Jin Y, Qian G, Tu H. A seventeen-year prospective cohort study on association of hepatitis
B virus e antigen with the risk of hepatocellular carcinoma. Tumor 2011;31:841-5.
33. Sun Y, Chen T, Lu P, Wang J, Wu Y, Zhang Q, Qian G, Tu H. Relationship between serum hepatitis B virus DNA load and hepatocellular
carcinoma in Qidong, China: a cohort follow-up study of 14 years. Natl Med J China 2012;92:1874-7.