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Page 4 of 10                                                  Iliescu et al. Hepatoma Res 2018;4:3  I  http://dx.doi.org/10.20517/2394-5079.2017.48

                                          Distribution of patients by gender and degree of fibrosis






















                                       Figure 1. Distribution of patients by gender and degree of fibrosis

                          Distribution of patients with high AFP levels according to gender, fibrosis, and means of further evaluation
















                     Figure 2. The distribution of patients with high AFP levels, according to gender, fibrosis and means of further evaluation.
                             AFP: alpha-fetoprotein; CT: computed tomography; CEUS: contrast-enhanced ultrasonography

                                          Evolution of patients diagnosed with HCC on treatment





















                     Figure 3. Evolution of patients diagnosed with HCC on treatment. HCC: hepatocellular carcinoma; AFP: alpha-fetoprotein

               with single HCC nodule and PVT, and 1 patient with multiple HCC nodules and PVT). The direct antiviral
               therapy was not interrupted in any of the cases. The 3 subjects diagnosed with HCC and no signs of PVT
               underwent trans-arterial chemoembolization (TACE) with doxorubicin, while on antiviral therapy, with
               good outcome. Figure 3 reveals the evolution of the patients who were diagnosed with HCC during treatment.
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