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Cho et al. Hepatoma Res 2016;2:259-63 Hepatoma Research
DOI: 10.20517/2394-5079.2016.13
www.hrjournal.net
Topic: Advances in Minimally Invasive Cirrhotic Surgery Open Access

Laparoscopic liver resection for

hepatocellular carcinoma in patients with

cirrhosis

Jai Young Cho, Ho-Seong Han

Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul 463-707, South Korea.
Correspondence to: Dr. Ho-Seong Han, Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of
Medicine, 300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, Seoul 463-707, South Korea. E-mail: hanhs@snubh.org
How to cite this article: Cho JY, Han HS. Laparoscopic liver resection for hepatocellular carcinoma in patients with cirrhosis. Hepatoma Res
2016;2:259-63.

Dr. Ho-Seong Han is a Professor of Department of Surgery, Seoul National University Bundang Hospital, Seoul
National University College of Medicine. He graduated from Seoul National University College of Medicine in
1984, and finished internship and residency of Department of Surgery at Seoul National University Hospital
in 1989. His field of interest is hepatobiliary surgery and laparoscopic surgery. He performed laparoscopic
right posterior sectionectomy, central bisectionectomy for hepatocellular carcinoma as world-first. He has also
performed laparoscopic liver resection in pediatric patient and succeeded in total laparoscopic right side donor
hepatectomy as world-first. He plays an important role in many societies.

ABSTRACT
Article history: Hepatocellular carcinoma (HCC) is a common malignant tumor and many cases occur in
Received: 11-05-2016 patients with liver cirrhosis. Although liver transplantation is the most effective treatment
Accepted: 09-08-2016 option, hepatectomy is still the first curative treatment option because liver transplantation
Published: 30-09-2016 is limited by the donors and high cost. In recent years, laparoscopic liver resection (LLR)
has increasingly been performed in patients with liver cirrhosis, and has several advantages
Key words: over open liver resection. Besides less pain and shorter hospital stay, LLR in patients with
Laparoscopy, liver cirrhosis is also associated with lower incidences of postoperative liver failure and
hepatectomy, ascites because of greater preservation of collateral veins and less liver manipulation. With
cirrhosis, increasing experience, LLR for HCC located in segments 7 or 8 is now feasible, and anatomic
portal hypertension LLR could be performed in patients with cirrhosis. Many comparative studies have shown
that LLR is better than open liver resection in patients with liver cirrhosis in terms of a lower
incidence of postoperative liver failure and similar patient survival. In conclusion, LLR is a
promising treatment modality for HCC in patients with liver cirrhosis.

INTRODUCTION liver cancer, and the third most common cause of
[1]
cancer-related death worldwide. Most HCCs are
[2]
Hepatocellular carcinoma (HCC) is the fifth most found in patients with liver cirrhosis, although HCC
common malignant tumor, the most common primary occurs in 60-90% of all patients with liver cirrhosis. [3]
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