Page 55 - Read Online

2012;19:2869-76.
4. Groeschl RT, Turaga KK, Gamblin TC. Transplantation versus resection for
patients with combined hepatocellular carcinoma-cholangiocarcinoma.
J Surg Oncol 2013;107:608-12.
5. Park YH, Hwang S, Ahn CS, Kim KH, Moon DB, Ha TY, Song GW,
Jung DH, Park GC, Namgoong JM, Park CS, Park HW, Kang SH,
Jung BH, Lee SG. Long-term outcome of liver transplantation for
combined hepatocellular carcinoma and cholangiocarcinoma. Transplant
Proc 2013;45:3038-40.
6. Maganty K, Levi D, Moon J, Bejarano PA, Arosemena L, Tzakis A,
Martin P. Combined hepatocellular carcinoma and intrahepatic
cholangiocarcinoma: outcome after liver transplantation. Dig Dis Sci
2010;55:3597-601.
7. Garancini M, Goffredo P, Pagni F, Romano F, Roman S, Sosa JA,
Giardini V. Combined hepatocellular-cholangiocarcinoma:
a population-level analysis of an uncommon primary liver tumor. Liver
Transpl 2014;20:952-9.
8. Song S, Moon HH, Lee S, Kim TS, Shin M, Kim JM, Park JB,
Figure 3: Tumor (white arrows) during the transarterial chemoembolization
Kwon CH, Kim SJ, Lee SK, Joh JW. Comparison between resection
and transplantation in combined hepatocellular and cholangiocarcinoma.
The occurrence of a malignant liver disease in patients with Transplant Proc 2013;45:3041-6.
CF is rare. There are a few case reports of HCC in young CF 9. McKeon D, Day A, Parmar J, Alexander G, Bilton D. Hepatocellular
patients. [9-11] Beyond this, there is only one case report describing carcinoma in association with cirrhosis in a patient with cystic fi brosis.
J Cyst Fibros 2004;3:193-5.
a CC in a CF patient, who died soon after the diagnosis. [12] 10. Kelleher T, Staunton M, O’Mahony S, McCormick PA. Advanced
hepatocellular carcinoma associated with cystic fibrosis. Eur J
In this report, we present the first case describing a combined Gastroenterol Hepatol 2005;17:1123-4.
HCC and CC in cirrhotic liver caused by CF. After successful 11. O’Donnell DH, Ryan R, Hayes B, Fennelly D, Gibney RG.
LDLT, the patient remains disease-free . Hepatocellular carcinoma complicating cystic fi brosis related liver
disease. J Cyst Fibros 2009;8:288-90.
12. Tesluk H, McCauley K, Kurland G, Ruebner BH. Cholangiocarcinoma
REFERENCES in an adult with cystic fi brosis. J Clin Gastroenterol 1991;13:485-7.

1. Bruix J, Gores GJ, Mazzaferro V. Hepatocellular carcinoma: clinical
frontiers and perspectives. Gut 2014;63:844-55. How to cite this article: Rauchfuß F, Dondorf F, Fahrner R, Ardelt M,
Dittmar Y, Settmacher U. Successful living donor liver transplantation
2. Herrmann U, Dockter G, Lammert F. Cystic fi brosis-associated liver in a cystic fi brosis patient with combined hepatocellular carcinoma and
disease. Best Pract Res Clin Gastroenterol 2010;24:585-92. cholangiocarcinoma. Hepatoma Res 2015;1:46-8.
3. Yin X, Zhang BH, Qiu SJ, Ren ZG, Zhou J, Chen XH, Zhou Y,
Fan J. Combined hepatocellular carcinoma and cholangiocarcinoma: Source of Support: Nil. Confl ict of Interest: None declared.
clinical features, treatment modalities, and prognosis. Ann Surg Oncol

48 Hepatoma Research | Volume 1 | Issue 1 | April 15, 2015