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Figure 3. Joinpoint analysis of trends in age-standardized (world population) mortality rates from intrahepatic cholangiocarcinoma
(ICC) and extrahepatic cholangiocarcinoma (ECC) for men (filled circles) and women (open circles) at all ages. Data for nine selected
major countries, from 1995 to 2018 (according to data availability), are shown.
Differences in mortality trends for ICC and ECC indicate quantitatively different etiologies. Indeed, while
