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Page 6 of 12 Hiyama et al. Hepatoma Res 2021;7:44 https://dx.doi.org/10.20517/2394-5079.2021.21

Table 1. Cases with microscopically positive margin at surgery

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Age at diag. # AFP at diag. $ AFP before surgery Additional
No PRETEXT Stratum POSTEXT Surgery Post CTx Event Outcome
(month)/sex (ng/mL) (ng/mL) treatments
(Recurrence)
1 3/M III 606,740 3 III 3382 ExtR C
2 14/M IIIR1 332,580 3 II 762 ExtR I local (17 m) CTx (I), Radiation
3 38/M IV V2 375,480 3 III 4187 ExtL I local (13 m) LT, CTx (I) dead (62 m)
4 21/M IV V2 M1 1,280,000 4 IV 180,000 LH + C
MCT
5 26/F III 917,671 3 III 23,704 Nonan I local, lung (51 m) CTx (I) dead (86 m)
6 15/F IV 313,390 3 III 95 ExtL I local (17 m) CTx (I) dead (102 m: AML)
7 15/F IV F1 1,839,700 3 IV 275 Seg. I
5,6,7
8 20/M II 8522.8 2 II 204 Seg. 5, 6 LC
9 1/M II 253,900 1 - - RH LC
10 16/M IIIM1 428,235 4 III 772 ExtL C local (12 m) metastasec. SCT dead (71 m)
11 30/F IV F1 887,800 3 IV 320,860 ExtR + I local, lung (14 m) SCT dead (23 m)
partialS2
12 11/F III 185,090 3 III 7.1 ExtL C lung (11 m) CTx (I)
13 18/M IIIF1 358,000 3 III 2170 ExtR C
14 10/M II 175,000 2 II 87,120 RH LC
15 14/M IIP2V2 190,635 3 II unknown ExtL CPT11 local (16 m) CTx (CPT11)
16 5/M II 250,270 2 II 560,765 RH LC

17 12/M II 27,956 2 II 1113 RH (+ LC
S1)
18 53/M I R1 31,980 1 - - Nonan C peritoneum (16 CTx (C)
m)
19 13/M IV 581,710 3 III 92,441 ExtL I
20 3/M III 420,000 3 III 78.5 ExtL C
21 54/F I C1R1 40,659 1 - - Nonan LC local (6 m) - dead (17 m)
22 0/M II 411,300 2 2 unknown ExtR C
23 30/F IIIM1 411,362 4 3 11,108 ExtL C Lung (13 m) SCT

24 6/F III 386,976 3 3 unknown ExtR I
25 9/M IIIF1 2,480,700 3 3 68,180 ExtL CPT11 CTx (CPT-11)

# [22] $ [3]
PRETEXT (PRE-Treatment EXTent of tumor) was classified according to 2017 PRETEXT definition . The stratum definition is described in . Diag.: Diagnosis; M: male; F: female; ExtL: extended left hepatectomy;
ExtR: extended right hepatectomy; LH: left hepatectomy; RH: right hepatectomy; MCT: microcoagulation therapy; Nonan: nonanatomic resection; Seg: segmentectomy; S: segment; C: CITA regimen (cisplatin +