Page 204 - Read Online
P. 204
Asao et al. Extracell Vesicles Circ Nucleic Acids 2023;4:461-85 https://dx.doi.org/10.20517/evcna.2023.37 Page 23
108. Ronquist KG, Sanchez C, Dubois L, et al. Energy-requiring uptake of prostasomes and PC3 cell-derived exosomes into non-
malignant and malignant cells. J Extracell Vesicles 2016;5:29877. DOI PubMed PMC
109. Yan W, Wu X, Zhou W, et al. Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent
metabolic reprogramming of stromal cells. Nat Cell Biol 2018;20:597-609. DOI PubMed PMC
110. Zhang J, Lu S, Zhou Y, et al. Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via
exosomes. Proteomics 2017;17:1700103. DOI
111. Cao M, Isaac R, Yan W, et al. Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair
systemic glucose homeostasis and contribute to tumour growth. Nat Cell Biol 2022;24:954-67. DOI PubMed PMC
112. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-74. DOI PubMed
113. Liberti MV, Locasale JW. The warburg effect: how does it benefit cancer cells? Trends Biochem Sci 2016;41:211-8. DOI PubMed
PMC
114. Rorsman P, Ashcroft FM. Pancreatic β-cell electrical activity and insulin secretion: of mice and men. Physiol Rev 2018;98:117-214.
DOI PubMed PMC
115. Ostenson CG, Gaisano H, Sheu L, Tibell A, Bartfai T. Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide
attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients. Diabetes 2006;55:435-40. DOI PubMed
116. Gallagher EJ, Zelenko Z, Neel BA, et al. Elevated tumor LDLR expression accelerates LDL cholesterol-mediated breast cancer
growth in mouse models of hyperlipidemia. Oncogene 2017;36:6462-71. DOI PubMed PMC
117. Hopkins BD, Pauli C, Du X, et al. Suppression of insulin feedback enhances the efficacy of PI3K inhibitors. Nature 2018;560:499-
503. DOI PubMed PMC
118. Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006;444:840-6.
DOI PubMed
119. Saltiel AR, Olefsky JM. Inflammatory mechanisms linking obesity and metabolic disease. J Clin Invest 2017;127:1-4. DOI PubMed
PMC
120. Barone BB, Yeh HC, Snyder CF, et al. Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: a
systematic review and meta-analysis. JAMA 2008;300:2754-64. DOI PubMed PMC
121. Tsilidis KK, Kasimis JC, Lopez DS, Ntzani EE, Ioannidis JP. Type 2 diabetes and cancer: umbrella review of meta-analyses of
observational studies. BMJ 2015;350:g7607. DOI PubMed
122. Xu J, Sun Y, Gong D, Fan Y. Impact of preexisting diabetes mellitus on cardiovascular and all-cause mortality in patients with atrial
fibrillation: a meta-analysis. Front Endocrinol 2022;13:921159. DOI PubMed PMC
123. Dong S, Wang Z, Shen K, Chen X. Metabolic Syndrome and breast cancer: prevalence, treatment response, and prognosis. Front
Oncol 2021;11:629666. DOI PubMed PMC
124. Peairs KS, Barone BB, Snyder CF, et al. Diabetes mellitus and breast cancer outcomes: a systematic review and meta-analysis. J Clin
Oncol 2011;29:40-6. DOI PubMed PMC
125. Shahid RK, Ahmed S, Le D, Yadav S. Diabetes and cancer: risk, challenges, management and outcomes. Cancers 2021;13:5735.
DOI PubMed PMC
126. Wang G, Li J, Bojmar L, et al. Tumour extracellular vesicles and particles induce liver metabolic dysfunction. Nature 2023;618:374-
82. DOI PubMed
127. Phinney DG, Di Giuseppe M, Njah J, et al. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle
microRNAs. Nat Commun 2015;6:8472. DOI PubMed PMC
128. Sansone P, Savini C, Kurelac I, et al. Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in
hormonal therapy-resistant breast cancer. Proc Natl Acad Sci U S A 2017;114:E9066-75. DOI PubMed PMC
129. Finn OJ. Cancer immunology. N Engl J Med 2008;358:2704-15. DOI PubMed
130. Yin X, Zeng W, Wu B, et al. PPARα inhibition overcomes tumor-derived exosomal lipid-induced dendritic cell dysfunction. Cell Rep
2020;33:108278. DOI PubMed PMC
131. Kim DH, Kim H, Choi YJ, et al. Exosomal PD-L1 promotes tumor growth through immune escape in non-small cell lung cancer. Exp
Mol Med 2019;51:1-13. DOI PubMed PMC
132. Ricklefs FL, Alayo Q, Krenzlin H, et al. Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles. Sci Adv
2018;4:eaar2766. DOI PubMed PMC
133. Wen SW, Sceneay J, Lima LG, et al. The biodistribution and immune suppressive effects of breast cancer-derived exosomes. Cancer
Res 2016;76:6816-27. DOI PubMed
134. Jiang Z, Zhang Y, Zhang Y, Jia Z, Zhang Z, Yang J. Cancer derived exosomes induce macrophages immunosuppressive polarization
to promote bladder cancer progression. Cell Commun Signal 2021;19:93. DOI PubMed PMC
135. Morrissey SM, Zhang F, Ding C, et al. Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche
through glycolytic dominant metabolic reprogramming. Cell Metab 2021;33:2040-58.e10. DOI PubMed PMC
136. Popēna I, Ābols A, Saulīte L, et al. Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine
secretion profile of monocytes and macrophages. Cell Commun Signal 2018;16:17. DOI PubMed PMC
137. Yin Y, Liu B, Cao Y, et al. Colorectal cancer-derived small extracellular vesicles promote tumor immune evasion by upregulating
PD-L1 expression in tumor-associated macrophages. Adv Sci 2022;9:2102620. DOI PubMed PMC
138. Shin S, Ko H, Kim CH, et al. Curvature-sensing peptide inhibits tumour-derived exosomes for enhanced cancer immunotherapy. Nat

