Page 131 - Read Online

Page 251 Raposo et al. Extracell Vesicles Circ Nucleic Acids 2023;4:240-54 https://dx.doi.org/10.20517/evcna.2023.18

DECLARATIONS
Acknowledgments
The authors would like to thank members of the team Structure and Membrane Compartments, Institut
Curie, and CNRS UMR144 for their continuous support and in particular Gisela d’Angelo for discussions
and ongoing work. We are indebted to Guillaume van Niel (INSERM, IPNP, Paris, France) for enriching
exchanges, conceptual models, and enthusiasm in the field. Thanks to Sharon M Stahl for helpful comments
and editing and Steve Graepel for designing the Figure.

Author’s Contributions
Conceived the idea for the manuscript: Raposo G, Stahl P
Wrote, revised, and edited the manuscript: Raposo G, Stahl P
Prepared Figure1: Stahl P, Graepel S
Prepared Figures 2, 3: Raposo G, Graepel S

Availability of Data and Materials
Not applicable.

Financial Support and Sponsorship
This research was supported in part by the National Institutes of Health (NIH) (Award numbers R01
EY015625 and R01 GM143774); as well as CNRS, Institut Curie, Fondation pour la Recherche Medicale,
and espoirs de la recherche (FRM 2020-2023).

Conflict of Interests
All authors declared that there are no conflicts of interest.

Ethical Approval and Consent to Participate
Not applicable.

Consent for Publication
Not applicable.

Copyright
© The Author(s) 2023.

REFERENCES
1. Duve C, Wattiaux R. Functions of lysosomes. Annu Rev Physiol 1966;28:435-92. DOI PubMed
2. Duve C. The significance of lysosomes in pathology and medicine. Proc Inst Med Chic 1966;26:73-6. PubMed
3. Brown MS, Goldstein JL. Michael S. Brown, MD, Joseph L. Goldstein, MD. 1985 Nobel laureates in medicine. J Investig Med
1996;44:14-23. PubMed
4. Schekman R, Novick P. 23 genes, 23 years later. Cell 2004;116:S13-5, 1 p following S19. DOI PubMed
5. Couch Y, Buzàs EI, Di Vizio D, et al. A brief history of nearly EV-erything - the rise and rise of extracellular vesicles. J Extracell
Vesicles 2021;10:e12144. DOI PubMed PMC
6. Niel G, D'Angelo G, Raposo G. Shedding light on the cell biology of extracellular vesicles. Nat Rev Mol Cell Biol 2018;19:213-28.
DOI PubMed
7. Niel G, Carter DRF, Clayton A, Lambert DW, Raposo G, Vader P. Challenges and directions in studying cell-cell communication by
extracellular vesicles. Nat Rev Mol Cell Biol 2022;23:369-82. DOI PubMed
8. Cicero A, Stahl PD, Raposo G. Extracellular vesicles shuffling intercellular messages: for good or for bad. Curr Opin Cell Biol
2015;35:69-77. DOI PubMed
9. Stegmayr B, Ronquist G. Promotive effect on human sperm progressive motility by prostasomes. Urol Res 1982;10:253-7. DOI
PubMed
10. Pan YC, Johnstone RM. Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of