Page 80 - Read Online

Nickoloff et al. Cancer Drug Resist 2021;4:244-63 I http://dx.doi.org/10.20517/cdr.2020.89 Page 256

Availability of data and materials
Not applicable.

Financial support and sponsorship
Research in the Nickoloff lab was supported by NIH (R01 GM084020); American Lung Association
grant (LCD-686552); CSU Office of the Vice President for Research; and the Japan National Institute of
Radiological Sciences Open Laboratory program. Research in the Kato lab was supported by the Dr. Akiko
Ueno Radiobiology Research fund.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2021.

REFERENCES
1. Otter SJ, Stewart AJ, Devlin PM. Modern brachytherapy. Hematol Oncol Clin North Am 2019;33:1011-25.
2. Daguenet E, Louati S, Wozny AS, et al. Radiation-induced bystander and abscopal effects: important lessons from preclinical models. Br
J Cancer 2020;123:339-48.
3. Halperin EC, Wazer DE, Perez CA, Brady LW. Perez & Brady’s Principles and Practice of Radiation Oncology. Lippincott Williams &
Wilkins; 2018. p. 24.
4. Mounier NM, Abdel-Maged AE, Wahdan SA, Gad AM, Azab SS. Chemotherapy-induced cognitive impairment (CICI): An overview of
etiology and pathogenesis. Life Sci 2020;258:118071.
5. Delou JMA, Souza ASO, Souza LCM, Borges HL. Highlights in resistance mechanism pathways for combination therapy. Cells
2019;8:1013.
6. Sato K, Shimokawa T, Imai T. Difference in acquired radioresistance induction between repeated photon and particle irradiation. Front
Oncol 2019;9:1213.
7. Ali MY, Oliva CR, Noman ASM, et al. Radioresistance in glioblastoma and the development of radiosensitizers. Cancers 2020;12:2511.
8. Zhan Y, Fan S. Multiple mechanisms involving in radioresistance of nasopharyngeal carcinoma. J Cancer 2020;11:4193-204.
9. Thariat J, Hannoun-Levi JM, Sun Myint A, Vuong T, Gerard JP. Past, present, and future of radiotherapy for the benefit of patients. Nat
Rev Clin Oncol 2013;10:52-60.
10. Karpuz M, Silindir-Gunay M, Ozer AY. Current and future approaches for effective cancer imaging and treatment. Cancer Biother
Radiopharm 2018;33:39-51.
11. Ramos P, Bentires-Alj M. Mechanism-based cancer therapy: resistance to therapy, therapy for resistance. Oncogene 2015;34:3617-26.
12. Reisz JA, Bansal N, Qian J, Zhao W, Furdui CM. Effects of ionizing radiation on biological molecules--mechanisms of damage and
emerging methods of detection. Antioxid Redox Signal 2014;21:260-92.
13. Zou Z, Chang H, Li H, Wang S. Induction of reactive oxygen species: an emerging approach for cancer therapy. Apoptosis
2017;22:1321-35.
14. Mailloux RJ. An Update on Mitochondrial Reactive Oxygen Species Production. Antioxidants 2020;9:472.
15. Tubbs A, Nussenzweig A. Endogenous DNA damage as a source of genomic instability in cancer. Cell 2017;168:644-56.
16. Vilenchik MM, Knudson AG. Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer. Proc Natl
Acad Sci USA 2003;100:12871-6.
17. Mehta A, Haber JE. Sources of DNA double-strand breaks and models of recombinational DNA repair. Cold Spring Harb Perspect Biol
2014;6:a016428.
18. Yang W, Gao Y. Translesion and repair DNA polymerases: diverse structure and mechanism. Annu Rev Biochem 2018;87:239-61.
19. Allen C, Ashley AK, Hromas R, Nickoloff JA. More forks on the road to replication stress recovery. J Mol Cell Biol 2011;3:4-12.
20. Gaillard H, Garcia-Muse T, Aguilera A. Replication stress and cancer. Nat Rev Cancer 2015;15:276-89.
21. Zhang J, Walter JC. Mechanism and regulation of incisions during DNA interstrand cross-link repair. DNA Repair 2014;19:135-42.
22. Shaheen R, Faqeih E, Ansari S, et al. Genomic analysis of primordial dwarfism reveals novel disease genes. Genome Res 2014;24:291-9.