Page 29 - Read Online
P. 29
Seno et al. Cancer Drug Resist 2019;2:335-50 I http://dx.doi.org/10.20517/cdr.2019.01 Page 349
3. Cojoc M, Mäbert K, Muders MH, Dubrovska A. A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms.
Semin Cancer Biol 2015;31:16-27.
4. Cukierman E, Bassi DE. The mesenchymal tumor microenvironment: a drug-resistant niche. Cell Adh Migr 2012;6:285-96.
5. Borovski T, Beke P, van Tellingen O, Rodermond HM, Verhoeff JJ,et al. Therapy-resistant tumor microvascular endothelial cells
contribute to treatment failure in glioblastoma multiforme. Oncogene 2013;32:1539-48.
6. Borovski T, De Sousa E Melo F, Vermeulen L, Medema JP. Cancer stem cell niche: the place to be. Cancer Res 2011;71:634-9.
7. LaBarge MA. The difficulty of targeting cancer stem cell niches. Clin Cancer Res 2010;16:3121-9.
8. Chen L, Kasai T, Li Y, Sugii Y, Jin G, et al. A model of cancer stem cells derived from mouse induced pluripotent stem cells. PLoS One
2012;7:e33544.
9. Yan T, Mizutani A, Chen L, Takaki M, Hiramoto Y, et al. Characterization of cancer stem-like cells derived from mouse induced
pluripotent stem cells transformed by tumor-derived extracellular vesicles. J Cancer 2014;5:572-84.
10. Prieto-Vila M, Yan T, Calle AS, Nair N, Hurley L, et al. iPSC-derived cancer stem cells provide a model of tumor vasculature. Am J
Cancer Res 2016;6:1906-21.
11. Matsuda S, Yan T, Mizutani A, Sota T, Hiramoto Y, et al. Cancer stem cells maintain a hierarchy of differentiation by creating their
niche. Int J Cancer 2014;135:27-36.
12. Yan T, Mizutani A, Matsuda S, Murakami H, et al. Mutual dependence between cancer stem cells and their progenies: the niche created
by the progenies is sustaining cancer stem cells. Cancer Cell & Microenvironment 2014;1:4.
13. Krishnamurthy S, Dong Z, Vodopyanov D, Imai A, Helman JI, et al. Endothelial cell-initiated signaling promotes the survival and self-
renewal of cancer stem cells. Cancer Res 2010;70:9969-78.
14. Zhu TS, Costello MA, Talsma CE, Flack CG, Crowley JG, et al. Endothelial cells create a stem cell niche in glioblastoma by providing
NOTCH ligands that nurture self-renewal of cancer stem-like cells. Cancer Res 2011;71:6061-72.
15. Calabrese C, Poppleton H, Kocak M, Hogg TL, Fuller C, et al. A perivascular niche for brain tumor stem cells. Cancer Cell 2007;11:14.
16. Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, et al. The perivascular niche regulates breast tumour dormancy. Nat Cell Biol
2013;15:807-17.
17. Jeon HM, Kim SH, Jin X, Park JB, Joshi K, et al. Crosstalk between glioma-initiating cells and endothelial cells drives tumor
progression. Cancer Res 2014;74:4482-92.
18. Okita K, Ichisaka T, Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007;448:313-7.
19. Nitiss JL. Targeting DNA topoisomerase II in cancer chemotherapy. Nat Rev Cancer 2009;9:338-50.
20. Nakajima W, Tanaka N. Noxa induces apoptosis in oncogene-expressing cells through catch-and-release mechanism operating between
Puma and Mcl-1. Biochem Biophys Res Commun 2011;413:643-8.
21. Li M, He Y, Dubois W, Wu X, Shi J, et al. Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA
damage response genes in embryonic stem cells. Mol Cell 2012;46:30-42.
22. Lin T, Chao C, Saito S, Mazur SJ, Murphy ME, et al. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog
expression. Nat Cell Biol 2005;7:165-71.
23. Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, et al. A caspase-activated DNase that degrades DNA during apoptosis, and
its inhibitor ICAD. Nature 1998;391:43-50.
24. Wolf BB, Schuler M, Echeverri F, Green DR. Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA
fragmentation factor-45/inhibitor of caspase-activated DNase inactivation. J Biol Chem 1999;274:30651-6.
25. McIlroy D, Sakahira H, Talanian RV, Nagata S. Involvement of caspase 3-activated DNase in internucleosomal DNA cleavage induced
by diverse apoptotic stimuli. Oncogene 1999;18:4401-8.
26. Tichy ED, Stephan ZA, Osterburg A, Noel G, Stambrook PJ. Mouse embryonic stem cells undergo charontosis, a novel programmed
cell death pathway dependent upon cathepsins, p53, and EndoG, in response to etoposide treatment. Stem Cell Res 2013;10:428-41.
27. Li LY, Luo X, Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 2001;412:95-9.
28. Alexander YG, Wang G, Bogdan SA, Cynthia S-RM, Mark SE, et al. Role of DNAS1L3 in Ca2+- and Mg2+-dependent cleavage of
DNA into oligonucleosomal and high molecular mass fragments. Nucleic Acids Research 1999;27:1999–2005.
29. Yakovlev AG, Wang G, Stoica BA, Boulares HA, Spoonde AY, et al. A role of the Ca2+/Mg2+-dependent endonuclease in apoptosis and
its inhibition by Poly(ADP-ribose) polymerase. J Biol Chem 2000;275:21302-8.
30. Boulares AH, Zoltoski AJ, Contreras FJ, Yakovlev AG, Yoshihara K, et al. Regulation of DNAS1L3 endonuclease activity by poly(ADP-
ribosyl)ation during etoposide-induced apoptosis. Role of poly(ADP-ribose) polymerase-1 cleavage in endonuclease activation. J Biol
Chem 2002;277:372-8.
31. Shiokawa D, Shika Y, Araki S, Sunaga S, Mizuta R, et al. Stage-specific expression of DNasegamma during B-cell development and its
role in B-cell receptor-mediated apoptosis in WEHI-231 cells. Cell Death Differ 2007;14:992-1000.
32. Widlak P, Garrard WT. Ionic and cofactor requirements for the activity of the apoptotic endonuclease DFF40/CAD. Mol Cell Biochem
2001;218:125-30.
33. Wang R, Chadalavada K, Wilshire J, Kowalik U, Hovinga KE, et al. Glioblastoma stem-like cells give rise to tumour endothelium.
Nature 2010;468:829-33.
34. Ricci-Vitiani L, Pallini R, Biffoni M, Todaro M, Invernici G, et al. Tumour vascularization via endothelial differentiation of
glioblastoma stem-like cells. Nature 2010;468:824-8.
35. Soda Y, Marumoto T, Friedmann-Morvinski D, Soda M, Liu F, et al. Transdifferentiation of glioblastoma cells into vascular endothelial
cells. Proc Natl Acad Sci U S A 2011;108:4274-80.