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Page 221                                                                                                                                                    Dababneh et al. Art Int Surg 2024;4:214-32  https://dx.doi.org/10.20517/ais.2024.50



                          Table 2. Compilation of published articles focusing on automated fracture detection in the hand or wrist using ML models

                          Study           Fracture site                          Dataset size (view)       ML model used                                        AUC               Sensitivity            Specificity
                          Olczak et al.   Wrist or hand or ankle                 256,000                   Multiple DL networks (BVLC Reference CaffeNet network,  0.83           -                  -
                                [25]
                          (2017)                                                                           VGG CNN S network, VGG CNN, Network-in-network)
                          Lee et al.      Distal radius, ulnar styloid or scaphoid  5,618 (AP, lat, and oblique) e-CRF, self-developed AI model                 Distal radius:    Distal radius: 0.97   Distal radius: 0.83
                                 [26]
                          (2023)                                                                                                                                0.903             Ulnar styloid:0.98   Ulnar styloid:0.87
                                                                                                                                                                Ulnar styloid:    Scaphoid: 0.87     Scaphoid: 0.74
                                                                                                                                                                0.925
                                                                                                                                                                Scaphoid: 0.808
                          Lindsey et al.   Wrist                                 34,990 (PA, lat)          Self-developed deep neural network                   0.954             0.94               0.95
                                [27]
                          (2018)
                          Cohen et al.    Distal radius or ulnar styloid or distal ulna   1,917 (AP, lat, oblique,   BoneView (Gleamer) DCNN algorithm          -                 0.83               0.96
                                 [28]
                          (2023)          or metacarpal or scaphoid or carpal bone  specific views of the
                                                                                 carpus)
                          Hardalac et al.  Distal radius or distal ulna          542                       WFD-C, deep-learning-based object detection model    0.864             -                  -
                                 [29]
                          (2022)
                          Alammar et al.   Humerus or wrist                      10,558                    TL adaption of ImageNet models                       Humerus: 0.879    Humerus: 0.87      Humerus: 0.87
                                 [31]
                          (2023)                                                                                                                                Wrist: 0.856      Wrist: 0.89        Wrist: 0.93
                          Jacques et al.   Distal radius or distal ulna or carpal bones  788               BoneView (Gleamer)                                   0.764             0.70               0.89
                                 [32]
                          (2024)          or scaphoid or finger
                          Kim and         Distal radius or distal ulna           1,489 (lat)               Inception v3 network, DCNNs                          0.954             0.90               0.88
                          MacKinnon
                                [33]
                          (2018)
                          Gan et al.      Distal radius                          2340 wrist (AP)           Inception-v4                                         0.96              0.90               0.96
                                [34]
                          (2019)
                          Oka et al.      Distal radius, styloid process of ulna  1,464 (AP, lat)          VGG16                                                Distal radius: 0.99  Distal radius: 0.99  Distal radius: 0.97
                                [36]
                          (2021)                                                                                                                                Ulna: 0.96        Ulna: 0.92         Ulna: 0.90
                          Russe et al.    Distal radius                          2,856 (AP, lat)           Xception                                             0.97              0.95               0.95
                                 [37]
                          (2024)
                          Zhang et al.    Distal radius                          6,536 (AP, lat)           Ensemble model of RetinaNet, Faster RCNN and Cascade  0.97             0.96               0.98
                                 [38]
                          (2023)                                                                           RCNN
                          Anttila et al.   Distal radius                         3,785 (PA, lat)           Self-developed DL algorithm developed as standalone   0.95             0.86               0.89
                                 [39]
                          (2023)                                                                           MATLAB application
                          Mert et al.     Distal radius                          150 (AP, lat)             ChatGPT 4                                            0.93              0.88               0.98
                                 [40]
                          (2024)
                          Ozkaya et al.   Scaphoid                               390 (AP)                  Pre-trained ResNet50 network                         0.84              0.76               0.92
                                 [41]
                          (2022)
                          Hendrix et al.   Scaphoid                              4,229 (AP, PA)            Self-developed fracture detection and segmentation CNN  0.87           0.78               0.84
                                [42]
                          (2021)
                          Hendrix et al.   Scaphoid                              19,111 (AP, PA, ulnar-    Self-developed fracture detection and segmentation CNN  0.88           0.72               0.93
                                 [43]
                          (2023)                                                 deviated and oblique)
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