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 Table 1. Main table describing study characteristics

 Mean     Comparison                                         Neural
 Paper  Dataset details  Imaging Model details absolute   Correlation   Accuracy metrics with other   Key   Validation   network   Batch  No. of
                                                                            size
                                                                                   epochs
                            limitations
                                           approach
 coefficient
 error    methods                                            architecture
 Chae et al.  Training - 400;   X-ray  Decentralized   1.45°-3.52° NA  Mean absolute error:  Compared to   Requires   40 test   Custom   NA  Initial:
 [18]
 2020  resolution - 3,240 ×   CNN; multiple   1.45°-3.52° for   manual   multiple ordered  radiographs;   decentralized   0.001,
 1,080 pixels; variety -   orders  parameters  measurement by   datasets,   comparison to   CNN  SGDM
 57% normal spine,   experienced   training time;   manual                         momentum
 20% lumbar lordosis,   surgeons, as well  limited diversity measurements by       0.95
 24% thoracic kyphosis  as regression      experienced
          CNN model                        surgeons
 Wu et al.   526 (154 patients);   X-ray  Custom MVC-  Landmark:  NA  Mean absolute error  Compared to   Single clinic   10-fold patient-  Custom MVC- 100  Starting:
 [19]
 2018  resolution: 128 × 256   Net  0.0398-  (landmark): 0.0398  manual   dataset; no   wise cross-  Net  0.01, halved
 pixels  0.0459;   (AP) - 0.0459   measurement and  metal artifact   validation;   every 10
 Cobb:   (LAT); circular mean  other deep   images  comparison to                  epochs
 4.04°-  absolute error (Cobb  learning methods  manual “gold
 4.07°  angle): 4.04° (AP) -               standard”
 4.07° (LAT)
 Wang et   526; resolution:   X-ray  Custom MVE-  Cobb:   NA  Circular mean   Compared to   Single clinic   Used same   Custom MVE- NA  Starting:
 [20]
 al. 2019  0.26 mm/pixel  Net  6.26°-7.81°  absolute error (Cobb  manual   dataset  dataset as   Net  0.01
 angle): 7.81° (AP) -   measurement and    previous study;
 6.26° (LAT); SMAPE  other deep            compared to other
 (Cobb angle):   learning methods          deep learning
 24.94% (AP) -                             methods
 11.90% (LAT)

 Zhang et   2,738 pairs (AP & LAT  X-ray  Custom MPF-  Landmark:  NA  Scaled mean   Compared to   Single clinic   10-fold cross-  Custom MPF- 120  Initial:
 [21]
 al. 2022  X-rays); from local   Net  0.0046-  absolute error   manual   dataset  validation;   Net  0.001,
 hospital  0.0050;   (landmark): 0.0046  measurement and   comparison to           decayed by
 Cobb:   (AP) - 0.0050   other deep        manual “gold                            0.2 every 30
 3.52°-4.05°  (LAT); circular mean  learning methods  standard”                    epochs
 absolute error (Cobb                      measurements
 angle): 3.52° (AP) -
 4.05° (LAT); SMAPE
 (Cobb angle):
 13.71% (AP) -
 12.60% (LAT)
 Zerouali  100 patients with   X-ray  SmartXpert   ≤ 2.9° or ≤  ≥ 0.85 except  Mean absolute error:  Compared to   Mainly pediatric  Comparison to   NA  NA  NA
 et al.   coronal & sagittal   (Milvue)  2.7 mm  thoracic   ≤ 2.9° or ≤ 2.7 mm   measurements by  population,   “gold standard”
 [22]
 2023  whole spine   kyphosis =   for parameters;   senior   exclusions   manual
 radiographs  0.58  intraclass correlation  musculoskeletal   restricted   measurements;
 coefficient: ≥ 0.85   radiologist   analysis to   visual assessment
 except thoracic   (ground truth)  preoperative   of reliability by
 kyphosis = 0.58            patients       radiologists
 Korez et   145 images to train   X-ray  RetinaNet + U-  1.2°-5.0°  NA  Mean absolute   Compared to   Single center   Statistical analysis  RetinaNet + U- NA  NA
 [23]
 al. 2020  model, 97 test images   Net CNNs  difference vs. manual  manual   data; did not   (mean absolute   Net
 with variety of   measurements: 1.2°- measurements by  evaluate intra-  difference,
 conditions  5.0° for parameters  spine surgeon   observer   correlation
   82   83   84   85   86   87   88   89   90   91   92