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Vakhtangadze et al. Vessel Plus 2019;3:19 Vessel Plus
DOI: 10.20517/2574-1209.2019.07

Review Open Access

The link between hypertension and preeclampsia/
eclampsia-life-long cardiovascular risk for women

Tamar Vakhtangadze , Nino Gakhokidze , Magda Khutsishvili , Salome Mosidze 2
1
3
2
1 Research Institute of Clinical Medicine, Caucasus International University, Tbilisi 0113, Georgia.
2 Tbilisi State Medical University, Tbilisi 0186, Georgia.
3 Department Propedeutics of Internal Diseases, David Tvildiani Medical University, Tbilisi 0159, Georgia.

Correspondence to: Prof. Tamar Vakhtangadze, Research Institute of Clinical Medicine, Caucasus International University,
Tevdore Mgvdeli street 13, Tbilisi 0113, Georgia. E-mail: tamarvakh@yahoo.com

How to cite this article: Vakhtangadze T, Gakhokidze N, Khutsishvili M, Mosidze S. The link between hypertension and preeclampsia/
eclampsia-life-long cardiovascular risk for women. Vessel Plus 2019;3:19. http://dx.doi.org/10.20517/2574-1209.2019.07

Received: 30 Nov 2018 First Decision: 5 Feb 2019 Revised: 14 Feb 2019 Accepted: 15 Feb 2019 Published: 31 May 2019

Science Editor: Alexander N. Orekhov Copy Editor: Cai-Hong Wang Production Editor: Huan-Liang Wu

Abstract
Cardiovascular diseases remain the main cause of death and morbidity in women. Despite the active preventive measures
and the reduction in the total number of morbidity and mortality rates, the rate of cardiovascular morbidity remains high
in the population, moreover cardiovascular morbidity is increased in women of 35-54 years. Cardiovascular morbidity
has several unique characteristics for women; pregnancy, gestational hypertension, preeclampsia/eclampsia are gender-
specific risk-factors for further cardiovascular morbidity in women, it's possible to detect these risk-factors in younger age
groups and start prevention as early as possible. Arterial hypertension, which is characterized by genetic polymorphism,
is an important and a powerful risk factor for development of both acute and chronic cardiovascular diseases; association
of arterial hypertension with different metabolic disorders suah as metabolic syndrome, diabetes seems particularly
dangerous in pregnancy in terms of peri-pregnancy and life-long morbidity. Preeclampsia shares some common features
with atherogenesis and metabolic changes and atherogenesis and metabolic changes, so presence of hypertension
during pregnancy increases the risk of cardiovascular diseases and diabetes later in the life. Is pregnancy revealing or
predisposing factor of development cardiovascular diseases is not still clear and to answer these questions more and
more studies are required.

Keywords: Arterial hypertension, women, pregnancy, cardiovascular risk

INTRODUCTION
[1,2]
Cardiovascular diseases remain the main cause of death and morbidity in women . Despite the active
preventive measures and the reduction in the total number of morbidity and mortality rates, the rate of
© The Author(s) 2019. Open Access This article is licensed under a Creative Commons Attribution 4.0
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