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Nikolay et al. Vessel Plus 2018;2:35 I http://dx.doi.org/10.20517/2574-1209.2018.45 Page 5 of 8

Table 3. Patients metabolic disorders in clinical groups
Metabolic changes OO EP HS P
Fasting glucose level, mmol/L 7.13 ± 1.9 7.32 ± 1.9 6.34 ± 2.5 0.02
Cholesterol, mmol/L 6.79 ± 1.1 7.73 ± 1.6 6.66 ± 1.7 0.001
Triglycerides, mmol/L 1.77 ± 0.8 2.08 ± 1.4 3.33 ± 1.4 0.001
Low-density lipoproteins, mmol/L 4.08 ± 1.1 4.49 ± 1.2 3.77 ± 1.5 0.02
High-density lipoproteins, mmol/L 0.92 ± 0.3 1.08 ± 0.4 1.05 ± 0.3 0.06
Atherogenicity coefficient 7.23 ± 2.7 6.67 ± 2.6 5.38 ± 2.8 0.01
Body mass index 27.88 ± 3.6 28.48 ± 3.6 28.17 ± 2.7 0.43
sBP, mmHg 148.45 ± 18.1 153.47 ± 20.5 156.00 ± 20.3 0.03
dBP, mmHg 86.29 ± 8.3 79,64 ± 13.2 85.88 ± 7.1 0.001
ABI 0.40 ± 0.1 0.43 ± 0.1 0.39 ± 0.1 0.28

sBP: systolic blood pressure; dBP: diastolic blood pressure; ABI: ankle-brachial index; OO: open operative; EP: endovascular procedures;
HS: hybrid surgery techniques

It should be noted that significant metabolic changes were registered in all analyzed groups, including
significant disturbances of carbohydrate and lipid metabolism. But with a severe lipid balance violation, the
method of choice for intervention was conventional.

The blood loss during hybrid interventions was significantly less than in the case of open reconstruction
operations: this circumstance is especially significant considering the comorbid characteristics of patients
from the OO group.

The time of patients’ stay in the intensive care unit was shortest after endovascular interventions and longest
after open methods of reconstruction. Hemodynamic instability was often noted after open operations.

As a result of hybrid surgery, there was no need for re-intervention and amputations. The primary patency of
the operated segment in this group in the early postoperative period was 100%.

The postoperative period after open reconstructions was characterized by a relatively high incidence
of complications: thrombosis of the operated segment and surgical site infection. Among patients who
underwent hybrid interventions such negative outcomes were not recorded.

The number of perioperative myocardial infarctions were not different in groups of OO and EP with
significant invasiveness of open surgery.

Features of the perioperative period are indicated in Table 4.

When analyzing the results of revascularization, depending on the degree of ischemia according to Fontein-
Pokrovsky classification, the complicated course of the postoperative period prevailed in cases of critical
ischemia [Table 5].

DISCUSSION
Data on the effectiveness of various revascularization techniques for lesions of the femoral-popliteal segment
are ambiguous: some authors state the best primary patency of shunting surgeries and the worst results of
endovascular techniques: low values of primary patency (58%), high percentage of limb loss one year after
[10]
surgery . Other authors consider endovasal interventions as the method of choice in the distal type of
lesion [11,12] . Data from several studies did not reveal a difference in the immediate outcomes of open and
[13]
endovascular surgical interventions .