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Saxena et al. Vessel Plus 2022;6:15  https://dx.doi.org/10.20517/2574-1209.2021.96  Page 7 of 17



 event rate
 Counseling  Yes  Yes  Yes   Yes, expert counseling required Yes, pregnancy contraindicated: if
                                                         pregnancy occurs, termination should
                                                         be discussed
 Care during   Local hospital  Local hospital  Referral hospital  Expert center for pregnancy   Expert center for pregnancy and cardiac
 pregnancy                   and cardiac disease         disease
 Minimal follow-up   Once or twice  Once per trimester  Bimonthly   Monthly or bimonthly  Monthly
 visits during
 pregnancy
 Location of delivery  Local hospital  Local hospital  Referral hospital  Expert center for pregnancy   Expert center for pregnancy and cardiac
                             and cardiac disease         disease

 ASI: Aortic size index; EF: ejection fraction; mWHO: modified World Health Organization classification; NYHA: New York Heart Association; WHO: World Health Organization.



 Assessment for other risk factors (parental obesity, diabetes, hypertension, infections, alcohol, smoking, and teratogenic medications) that can compromise

 fetal well-being and increase the risk of fetal birth defects should also be routinely done.


 Preconception counseling
 A multidisciplinary management plan should be devised and discussed with the patient and her family. It is extremely important in setting appropriate

 expectations and minimizing complications. In addition to the general recommendations, specific topics of discussion during counseling include education on
 maternal and fetal risks, pre-pregnancy optimization plan, modification of medications, planned schedule of cardiac evaluation and testing during pregnancy
 and in the peripartum time period, mode of delivery, and possible persistence of cardiovascular abnormalities after pregnancy when applicable.



 DIAGNOSIS OF CHD DURING PREGNANCY

 The physiological adaptations occurring during pregnancy make the clinical diagnosis of CHD challenging. It is usual to have some exertional dyspnea and
 fatigue during pregnancy. Edema of feet can be seen in 80% of healthy pregnant women. However, many disorders can be identified by a thorough history and
 physical examination. Unexplained dyspnea, pathological murmurs, presence of cyanosis, etc. must not be ignored as they are indicators of underlying CHD,
 and an echocardiography is indicated in these cases .
 [1]


 Echocardiography is a widely available imaging tool which gives diagnosis of CHD with great accuracy. Mild dilatation of cardiac chambers could be a normal

 finding during pregnancy. An exercise test, although best performed prior to planning pregnancy, can also be performed in asymptomatic pregnant patients
 with underlying CHD. It is recommended to perform a submaximal exercise to attain 80% of the predicted maximal heart rate . The developing fetus is
                                                             [1]
 vulnerable (highest during first trimester) to develop neurological abnormalities, growth restriction, and malignancies on ionizing radiation exposure, and,
 hence, chest radiograph and computed tomography must be avoided if possible [1,35] .
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