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Saxena et al. Vessel Plus 2022;6:15  https://dx.doi.org/10.20517/2574-1209.2021.96                                                                                      Page 7 of 17



                              event rate
                              Counseling          Yes                              Yes                          Yes                                 Yes, expert counseling required Yes, pregnancy contraindicated: if
                                                                                                                                                                                pregnancy occurs, termination should
                                                                                                                                                                                be discussed
                              Care during         Local hospital                   Local hospital               Referral hospital                   Expert center for pregnancy   Expert center for pregnancy and cardiac
                              pregnancy                                                                                                             and cardiac disease         disease
                              Minimal follow-up   Once or twice                    Once per trimester           Bimonthly                           Monthly or bimonthly        Monthly
                              visits during
                              pregnancy
                              Location of delivery  Local hospital                 Local hospital               Referral hospital                   Expert center for pregnancy   Expert center for pregnancy and cardiac
                                                                                                                                                    and cardiac disease         disease

                              ASI: Aortic size index; EF: ejection fraction; mWHO: modified World Health Organization classification; NYHA: New York Heart Association; WHO: World Health Organization.



                              Assessment for other risk factors (parental obesity, diabetes, hypertension, infections, alcohol, smoking, and teratogenic medications) that can compromise

                              fetal well-being and increase the risk of fetal birth defects should also be routinely done.


                              Preconception counseling
                              A multidisciplinary management plan should be devised and discussed with the patient and her family. It is extremely important in setting appropriate

                              expectations and minimizing complications. In addition to the general recommendations, specific topics of discussion during counseling include education on
                              maternal and fetal risks, pre-pregnancy optimization plan, modification of medications, planned schedule of cardiac evaluation and testing during pregnancy
                              and in the peripartum time period, mode of delivery, and possible persistence of cardiovascular abnormalities after pregnancy when applicable.



                              DIAGNOSIS OF CHD DURING PREGNANCY

                              The physiological adaptations occurring during pregnancy make the clinical diagnosis of CHD challenging. It is usual to have some exertional dyspnea and
                              fatigue during pregnancy. Edema of feet can be seen in 80% of healthy pregnant women. However, many disorders can be identified by a thorough history and
                              physical examination. Unexplained dyspnea, pathological murmurs, presence of cyanosis, etc. must not be ignored as they are indicators of underlying CHD,
                              and an echocardiography is indicated in these cases .
                                                                                        [1]


                              Echocardiography is a widely available imaging tool which gives diagnosis of CHD with great accuracy. Mild dilatation of cardiac chambers could be a normal

                              finding during pregnancy. An exercise test, although best performed prior to planning pregnancy, can also be performed in asymptomatic pregnant patients
                              with underlying CHD. It is recommended to perform a submaximal exercise to attain 80% of the predicted maximal heart rate . The developing fetus is
                                                                                                                                                                                    [1]
                              vulnerable (highest during first trimester) to develop neurological abnormalities, growth restriction, and malignancies on ionizing radiation exposure, and,
                              hence, chest radiograph and computed tomography must be avoided if possible               [1,35] .
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