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Page 4 of 7 Quin et al. Vessel Plus 2022;6:41 https://dx.doi.org/10.20517/2574-1209.2021.119

Table 1. Patient characteristics at the time of study enrollment
POAF No POAF
Baseline patient characteristics P-value
n = 551 n = 1552
Age in years (SD) 65.3 (8.5) 62.1 (8.2) < 0.01
Smoking status 154 (28%) 561 (36%) < 0.01
Chronic obstructive pulmonary disease 130 (24%) 297 (19%) 0.03
Serum Cr ≥ 1.5 59 (11%) 106 (6.8%) < 0.01
Stroke 47 (8.5%) 111 (7.1%) 0.29
Peripheral vascular disease 105 (19%) 218 (14%) < 0.01
Hypertension 494 (90%) 1318 (85%) < 0.01
Medically treated diabetes 218 (40%) 583 (38%) 0.41
Depression 62 (11%) 196 (13%) 0.46
Ejection fraction ≤ 45% 80 (15%) 263 (17%) 0.18
Urgent surgery 76 (14%) 251 (16%) 0.18
Aortic integrity 0.01
Good 402 (73%) 1225 (79%)
Moderate 107 (19%) 255 (16%)
Poor 34 (6.2%) 57 (3.7%)
Unknown 8 (1.4%) 15 (1.0%)
Number of grafts (SD) 3.0 (0.90) 2.95 0.93) 0.02

SD: Standard deviation; POAF: postoperative atrial fibrillation.

Figure 1. Unadjusted survival curves by year comparing ROOBY patients who developed POAF after surgery (1-blue line) vs. no POAF
(2-dotted red line); log-rank P-value = 0.0011.

serum creatinine > 1.5 (OR 0.33; 95%CI: 0.23-0.47), PVD (OR 0.45; 95%CI: 0.34-0.58) and smoking (OR
0.57; 95%CI: 0.46-0.72). No association was seen with hypertension (OR 0.89; 95%CI: 0.66-1.20) or POAF
(OR 0.95; 95%CI: 0.76-1.19).

DISCUSSION
This investigation found that, of the 26% of patient enrollees in the ROOBY trial who developed POAF after
CABG, approximately 19% had AF at 10 years; as such, these patients may benefit from counsel that there is
about a 1 in 5 chance of needing long-term anticoagulation and rate control. Patients who did not have