Page 50 - Read Online

Page 22 of 22 Strassheim et al. Vessel Plus 2018;2:29 I http://dx.doi.org/10.20517/2574-1209.2018.44

243. Weng M, Raher MJ, Leyton P, Combs TP, Scherer PE, Bloch KD, Medoff BD. Adiponectin decreases pulmonary arterial remodeling in
murine models of pulmonary hypertension. Am J Respir Cell Mol Biol 2011;45:340-7.
244. Hemnes AR, Rathinasabapathy A, Austin EA, Brittain EL, Carrier EJ, Chen X, Fessel JP, Fike CD, Fong P, Fortune N, Gerszten RE,
Johnson JA, Kaplowitz M, Newman JH, Piana R, Pugh ME, Rice TW, Robbins IM, Wheeler L, Yu C, Loyd JE, West J. A potential
therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension. Eur Respir J 2018;51.
245. Tozzi CA, Poiani GJ, McHugh NA, Shakarjian MP, Grove BH, Samuel CS, Unemori EN, Riley DJ. Recombinant human relaxin
reduces hypoxic pulmonary hypertension in the rat. Pulm Pharmacol Ther 2005;18:346-53.
246. Pintalhao M, Castro-Chaves P, Vasques-Novoa F, Goncalves F, Mendonca L, Fontes-Carvalho R, Lourenco P, Almeida P, Leite-Moreira
A, Bettencourt P. Relaxin serum levels in acute heart failure are associated with pulmonary hypertension and right heart overload. Eur J
Heart Fail 2017;19:218-25.
247. Imamura M, Vitello AM, Limbird JN, Ivy DD, Fallon MB, Carter EP. Endothelin-B receptor overexpression prevents hypoxic
pulmonary hypertension in cirrhotic rats. Chest 2005;128:580S-1S.
248. Reichenberger F, Voswinckel R, Steveling E, Enke B, Kreckel A, Olschewski H, Grimminger F, Seeger W, Ghofrani HA. Sildenafil
treatment for portopulmonary hypertension. Eur Respir J 2006;28:563-7.
249. Xiao R, Su Y, Feng T, Sun M, Liu B, Zhang J, Lu Y, Li J, Wang T, Zhu L, Hu Q. Monocrotaline induces endothelial injury and
pulmonary hypertension by targeting the extracellular calcium-sensing receptor. J Am Heart Assoc 2017;6:pii: e004865.
250. West JD, Voss BM, Pavliv L, de Caestecker M, Hemnes AR, Carrier EJ. Antagonism of the thromboxane-prostanoid receptor is
cardioprotective against right ventricular pressure overload. Pulm Circ 2016;6:211-23.
251. West JD, Carrier EJ, Bloodworth NC, Schroer AK, Chen P, Ryzhova LM, Gladson S, Shay S, Hutcheson JD, Merryman WD. Serotonin
2B receptor antagonism prevents heritable pulmonary arterial hypertension. PLoS One 2016;11:e0148657.
252. Tian W, Jiang X, Sung YK, Qian J, Yuan K, Nicolls MR. Leukotrienes in pulmonary arterial hypertension. Immunol Res 2014;58:387-
93.
253. Pyne NJ, Pyne S. Sphingosine kinase 1: a potential therapeutic target in pulmonary arterial hypertension? Trends Mol Med 2017;23:786-
98.
254. Sysol JR, Natarajan V, Machado RF. PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell
proliferation. Am J Physiol Cell Physiol 2016;310:C983-92.
255. Bhavanam NP, Failla A, Cho Y, Lockey RF, Kolliputi N. Commentary: the sphingosine kinase 1/sphingosine-1-phosphate pathway in
pulmonary arterial hypertension. Front Pharmacol 2015;6:229.