Page 379 - Read Online

Yang et al. Plast Aesthet Res 2020;7:34 I http://dx.doi.org/10.20517/2347-9264.2020.24 Page 9 of 10

J Psychosom Res 2012;72:282-87.
10. Hochman B, Isoldi FC, Furtado F, Ferreira LM. New approach to the understanding of keloid: psychoneuroimmune-endocrine aspects.
Clin Cosmet Investig Dermatol 2015;8:67-73.
11. Tan PL, Farmiloe S, Yeoman S, Watson JD. Expression of the interleukin 6 gene in rheumatoid synovial fibroblasts. J Rheumatol
1990;17:1608-12.
12. Feghali CA, Bost KL, Boulware DW, Levy LS. Control of IL-6 expression and response in fibroblasts from patients with systemic
sclerosis. Autoimmunity 1994;17:309-18.
13. Gurram M, Pahwa S, Frieri M. Augmented interleukin-6 secretion in collagen-stimulated peripheral blood mononuclear cells from
patients with systemic sclerosis. Ann Allergy 1994;73:493-96.
14. Shahar I, Fireman E, Topilsky M, Grief J, Kivity S, et al. Effect of IL-6 on alveolar fibroblast proliferation in interstitial lung diseases.
Clin Immunol Immunopathol 1996;79:244-51.
15. Chistyakov DV, Astakhova AA, Sergeeva MG. Resolution of inflammation and mood disorders. Exp Mol Pathol 2018;105:190-201.
16. Doucet C, Brouty-Boye D, Pottin-Clemenceau C, Canonica GW, Jasmin C, et al. Interleukin (IL) 4 and IL-13 act on human lung
fibroblasts. Implication in asthma. J Clin Invest 1998;101:2129-39.
17. Wynn TA. Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat Rev Immunol 2004;4:583-94.
18. Dasu MR, Hawkins HK, Barrow RE, Xue H, Herndon DN. Gene expression profiles from hypertrophic scar fibroblasts before and after
IL-6 stimulation. J Pathol 2004;202:476-85.
19. Tosa M, Watanabe A, Ghazizadeh M. IL-6 polymorphism and susceptibility to keloid formation in a Japanese population. J Invest
Dermatol 2016;136:1069-72.
20. Kiecolt-Glaser JK, Loving TJ, Stowell JR, Malarkey WB, Lemeshow S, et al. Hostile marital interactions, proinflammatory cytokine
production, and wound healing. Arch Gen Psychiatry 2005;62:1377-84.
21. Glaser R, Robles TF, Sheridan J, Malarkey WB, Kiecolt-Glaser JK. Mild depressive symptoms are associated with amplified and
prolonged inflammatory responses after influenza virus vaccination in older adults. Arch Gen Psychiatry 2003;60:1009-14.
22. Souza BR, Santos JS, Costa AM. Blockade of beta1- and beta2-adrenoceptors delays wound contraction and re-epithelialization in rats.
Clin Exp Pharmacol Physiol 2006;33:421-30.
23. Pelat M, Verwaerde P, Galitzky J, Lafontan M, Berlan M, et al. High isoproterenol doses are required to activate beta3-adrenoceptor-
mediated functions in dogs. J Pharmacol Exp Ther 2003;304:246-53.
24. de Mesquita CJG. About strawberry, crab claws, and the Sir James Black’s invention. Hypothesis: can we battle keloids with propranolol?
Med Hypotheses 2010;74:353-9.
25. Enoshiri T, Naitoh M, Yamawaki S, Kawaguchi A, Aya R, et al. β-adrenergic receptor blockers reduce the occurrence of keloids and
hypertrophic scars after cardiac device implantation: a single-institution case-control study. Plast Reconstr Surg 2017;139:1248-56.
26. Herndon D, Capek KD, Ross E, Jay JW, Prasai A, et al. Reduced postburn hypertrophic scarring and improved physical recovery with
yearlong administration of oxandrolone and propranolol. Ann Surg 2018;268:431-41.
27. Gonzalez-Cabrera PJ, Shi T, Yun J, McCune DF, Rorabaugh BR, et al. Differential regulation of the cell cycle by alpha1-adrenergic
receptor subtypes. Endocrinology 2004;145:5157-67.
28. Lei B, Schwinn DA, Morris DP. Stimulation of alpha1a adrenergic receptors induces cellular proliferation or antiproliferative hypertrophy
dependent solely on agonist concentration. PLoS One 2013;8:e72430.
29. Sterin-Borda L, Furlan C, Orman B, Borda E. Differential regulation on human skin fibroblast by alpha1 adrenergic receptor subtypes.
Biochem Pharmacol 2007;74:1401-12.
30. Waldrop BA, Mastalerz D, Piascik MT, Post GR. Alpha(1B)- and alpha(1D)-Adrenergic receptors exhibit different requirements
for agonist and mitogen-activated protein kinase activation to regulate growth responses in rat 1 fibroblasts. J Pharmacol Exp Ther
2002;300:83-90.
31. Drummond PD, Dawson LF, Wood FM, Fear MW. Up-regulation of alpha1-adrenoceptors in burn and keloid scars. Burns 2018;44:582-8.
32. Zhang H, Faber JE. Trophic effect of norepinephrine on arterial intima-media and adventitia is augmented by injury and mediated by
different alpha1-adrenoceptor subtypes. Circ Res 2001;89:815-22.
33. Faber JE, Szymeczek CL, Cotecchia S, Thomas SA, Tanoue A, et al. Alpha1-adrenoceptor-dependent vascular hypertrophy and
remodeling in murine hypoxic pulmonary hypertension. Am J Physiol Heart Circ Physiol 2007;292:H2316-23.
34. Pang X, Sun NL. Calcineurin-NFAT signaling is involved in phenylephrine-induced vascular smooth muscle cell proliferation. Acta
Pharmacol Sin 2009;30:537-44.
35. Zhang Q, Oh CK, Messadi DV, Duong HS, Kelly AP, et al. Hypoxia-induced HIF-1 alpha accumulation is augmented in a co-culture of
keloid fibroblasts and human mast cells: involvement of ERK1/2 and PI-3K/Akt. Exp Cell Res 2006;312:145-55.
36. Zhao B, Guan H, Liu JQ, Zheng Z, Zhou Q, et al. Hypoxia drives the transition of human dermal fibroblasts to a myofibroblast-like
phenotype via the TGF-beta1/Smad3 pathway. Int J Mol Med 2017;39:153-9.
37. Long F, Si L, Long X, Yang B, Wang XJ, et al. 2ME2 increase radiation-induced apoptosis of keloid fibroblasts by targeting HIF-1alpha
in vitro. Australas J Dermatol 2016;57:e32-8.
38. Touchi R, Ueda K, Kurokawa N, Tsuji M. Central regions of keloids are severely ischaemic. J Plast Reconstr Aesthet Surg 2016;69:e35-41.
39. Zhang Z, Nie F, Kang C, Chen B, Qin Z, et al. Increased periostin expression affects the proliferation, collagen synthesis, migration and
invasion of keloid fibroblasts under hypoxic conditions. Int J Mol Med 2014;34:253-61.
40. Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L. IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway
identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J 2003;17:2115-7.