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occipital nerve. inhibitory factors expressed by the extracellular matrix.

We are postulate that our results are due to the Based on our experience, we consider autologous fat grafting
induction of architectural remodeling and regeneration, as an innovative solution for neuropathic pain syndromes
neovascularization and improved hydration by fat grafting. that are related to scar retraction. The low complication rate
This leads tothe release of scar entrapment and anatomical and good results indicate that it should be considered as a
remodeling. effective treatment option.

We further evaluate the effect of autologous fat grafting on Financial support and sponsorship
[6]
nerve function in our recent case report where we describe Nil.
the case of a 45-year-old male patient who presented with
a retracted and painful scar in the nasolabial fold. This Conficts of interest
scar of traumatic origin was associated with partial motor There are no conflicts of interest.
impairment of the muscles of the mouth. We observed
complete restoration of movement with two cycles of REFERENCES
autologous fat grafting at the one year follow-up.
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The presence of mesenchymal multipotent stem cells in the principles of diagnosis and treatment. Plast Aesthet Res 2015;2:156-64.
adipocyte cell fraction of the graft have been demonstrated 2. Klinger FM, Vinci V, Forcellini D, Caviggioli F. Basic science review on adipose
histologically. These are cells that are responsible for scar 3. tissue for clinicians. Plast Reconstr Surg 2011;128:829-30.
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remodeling through engraftment and differentiation. B, Forcellini D, Maione L, Vinci V, Caviggioli F. Regenerative Approach to Scars,
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Caviggioli F, Maione L, Forcellini D, Klinger F, Klinger M. Autologous fat graft
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Furthermore, we hypothesize that autologous fat graft could Broggi G. Treatment of chronic headache of cervical origin with lipostructure:
induce molecular changes in the microenvironment of the an observational study. Headache 2013;53:507-13.
post-traumatic scar. This environment is otherwise hostile 6. Klinger M, Lisa A, Caviggioli F, Maione L, Murolo M, Vinci V, Klinger FM.
Autologous Fat Grafting Improves Facial Nerve Function. Case Rep Surg
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