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®
wall repair, PHASIX knitted mesh (Tepha) demonstrated CONCLUSION
burst strength significantly greater than native tissue at
all points up to one year. As with silk scaffolds, a variety The concept of an implantable internal bra continues to
[42]
of uses for constructs based on PHB have been explored, evolve. Third generation biomaterials designed to act as
including heart valves. Clinical trial results for GalaFLEX ® templates that resorb and initiate tissue neogenesis address
[43]
(P4HB mesh) in breast surgery have not yet been reported many of the issues posed by non-resorbable materials and
but a trial in mastopexy and reduction mammoplasty is acellular matrices, but have only recently become widely
ongoing. available and less is known about complication rates and
best practices. As indications become better defined and
A composite mesh comprised of fast-absorbing and slow- clinical experience grows, the use of these materials appears
absorbing fibers has also been explored (TIGR Matrix poised to usher in a new generation of regenerative surgery.
®
surgical mesh, Novus Scientific.) At an average follow-up
of 16 months, a favorable complication rate was observed Financial support and sponsorship
in a case series of breast reconstruction, revision implant Nil.
surgery, and primary aesthetic procedures.
[44]
Conflicts of interest
Because third generation meshes facilitate subcutaneous There are no conflicts of interest.
placement, mastopexy may be performed without
parenchymal disruption or reliance on a tight skin envelope.
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6 Plast Aesthet Res || Vol 3 || Issue 1 || Jan 15, 2016