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Ali et al. Plast Aesthet Res 2021;8:35  https://dx.doi.org/10.20517/2347-9264.2021.29  Page 3 of 15

               Table 1. Summary of prominent head and neck microvascular free tissue transfer reconstruction technologic advancements
                                       Brief Description
                Preoperative
                Computer tomography (CT)   Utilized CT angiograms for perforator mapping and MFTT design
                angiography
                Infrared thermography  Thermal sensors used to identify perforators
                Photoacoustic tomography  Utilizes a near infrared pulse laser and ultrasound to provide 3D mapping of subcutaneous vessels
                Color duplex ultrasonography  Ultrasound used for perforator mapping
                Medical modeling*      Use of preoperative imaging in modeling, planning, and plating for MFTT reconstruction
                Intraoperative
                Microvascular couplers  Alternative mode of vessel anastomosis to hand-suturing. Can be used with veins and arteries, with some
                                       limitations
                Three-dimensional (3D) exoscope  3D stereoscopic camera based viewing systems used as an alternative to operating microscopes and
                                       surgical loupes
                Fluorescent angiography  Assesses arterial perfusion and venous insufficiency of the flap through the fluorescence of the skin
                                       paddle
                Osseointegrated implants*  Immediate placement of implants into osseous MFTT for dental reconstruction
                Postoperative
                Implantable dopplers   Ultrasonic probe secured to the vascular pedicle provides real-time assessment of flow
                Color duplex doppler   Utilizes color doppler US to identify and trace the pedicle to assess vascular flow
                ultrasonography
                Near-infrared spectrophotoscopy  Light source emits energy at specific near-infrared wavelengths in order to measure relative changes in
                                       concentration of oxygenated and deoxygenated hemoglobin
                Laser doppler flowmetry  Fiber optic probe secured to the skin paddle for the purpose of measuring microcirculatory changes via an
                                       induced doppler shift
                Digital infrared surface thermometer  Thermometer monitors temperature changes in flap surface temperature
                monitoring

               *This topic is not discussed in this manuscript as it is covered in a separate section of this edition. CT: Computer tomography; MFTT:
               microvascular free tissue transfer; 3D: three-dimensional.


               between the CTA and non-CTA group. However, the CTA allowed them to choose the leg with more
               perforators or to choose septocutaneous perforators which may have contributed to decreased time of
               harvest. CTA also helped plan for more complex flaps that required two isolated paddles. Garvey et al.
                                                                                                         [9]
               reports a 74.1% sensitivity in identifying the presence of ALT perforators when CTA was obtained. In this
               dataset, CTA was better at localizing proximal perforators than distal. They also reported a 77.5% accuracy
               in determining a septocutaneous vs. musculocutaneous course of the perforator. The CTA influenced
               operative decision making in 37.5% of their overall cases and over half of their cases that would require two
               skin paddles.


               CTA has been described for harvest of TDAP flaps. Mun et al.  reported significantly decreased operative
                                                                    [10]
               duration and decreased length of incision when using preoperative perforator mapping. They recommend
               patients to be positioned similar to the intraoperative position at the time of imaging to allow for more
                                                                          [11]
               accurate marking of perforators at the time of surgery. Kim and Lee  recommend requesting 1 mm cuts
               when obtaining imaging to better visualize small perforators. They also recommend utilizing both the
                                                                                                  [11]
               coronal and axial cuts to identify perforators off the transverse and descending thoracodorsal artery .

               Lastly, for the vessel-depleted neck, dual-phase CT (delayed images to highlight venous vasculature) has
               proven useful in identifying arterial and venous targets, and even guiding the surgeon to consider a local or
               regional flap for reconstruction .
                                         [12]
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