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Ma et al. Plast Aesthet Res 2021;8:32 https://dx.doi.org/10.20517/2347-9264.2021.20 Page 7 of 8

Figure 2. Comparison of the circumference change between the control group and the multi-injection group. Negative numbers indicate
improvement. The circumference change of the upper limbs in the control group was -3.95% ± 1.34% and in the multi-injection group
was -6.96% ± 0.88% (*P < 0.05). The change in circumference of the lower limbs was -5.01% ± 2.2% in the multi-injection group and
-2.33% ± 1.77% in the control group (**P = 0.003).

may have contributed to shortening the surgical duration and the circumference reduction. Multipoint
injection ICG in lymphography is helpful for preoperative assessment of lymphatic function and
determination of lymphatic function in the whole limb.

DECLARATIONS
Authors’ contributions
Made substantial contributions to conception and design of the study and performed operation: Liu B, Ma
G
Provided technical, and material support: Han Y, Liu B
Performed operation and data acquisition: Ma G, Cui X, Wang W

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
The ethical committee of Xi’an Central Hospital, Medical School of Xi’an Jiaotong University approved this
study (LW-2021-011).