Page 30 - Read Online
P. 30

Page 8 of 13                                                                                   Wilson et al. Plast Aesthet Res. 2025;12:8   https://dx.doi.org/10.20517/2347-9264.2024.135



                                          [12]
                          Munasinghe et al.    2016          Case series     Burns & Trauma  11           Adult                       20%-85%      /                                    Mean % graft take
                                     [33]
                          Menon et al.         2013          Case series     Burns           7            Pediatric                   30%-70%      /                                    Mean number of surgical
                                                                                                                                                                                        procedures
                                         [18]
                          Danks and Lairet     2010          Case report     Journal of Burn   1          Adult                       54%          /                                    Length of stay
                                                                             Care and
                                                                             Research
                                       [19]
                          Lumenta et al.       2009          Case series     Journal of Burn   10         Adult                       > 60%        /                                    Time to heal
                                                                             Care and
                                                                             Research
                                    [17]
                          Hsieh et al.         2008          Case series     Burns           37           Adult                       40%-97%      /                                    % viability at POD 10
                                         [13]
                          Papp and Härmä       2003          Case series     Burns           3            Both                        76%-92%      /                                    % re-epithelialization at 4 weeks
                                                                                                                                                                                        post op
                                      [11]
                          Lari and Gang        2001          Case series     Burns           7            Both                        50%-85%      /                                    % Graft take at POD7
                                      [16]
                          Zermani et al.       1997          Retrospective   Burns           5            Both                        Average      /                                    % graft in situ POD6
                                                             cohort study                                                             35.6%
                                   [10]
                          Kreis et al.         1993          Case series     Burns           10           Both                        43%-83%      /                                    Mean % take at one week

                          BTM: Biodegradable temporising matrix; CEA: cultured epithelial allografts; TBSA: total body surface area; SSG/STSG: split thickness skin graft; POD: post operative day; PNI: prognostic nutrition index.



                          micrografting, allowing both tasks to be completed concurrently and improving overall efficiency.



                          Meek for larger burns
                          The modified Meek technique for treating larger burns is well established                [6-8,12,14,15,27] . For large TBSA burns with limited donor site availability, the ability to

                          cover as much area as possible, as quickly as possible, allows for larger burns to be treated with fewer procedures and a reduced need to re-crop donor sites.
                          Reports show that the overall Meek take rates range from 60%-100%, with the time to healing varying from 7 to 90 days. In our cohort, the mean length of stay
                          was 64 days, which is comparable to the literature range of 27 to 160 days, with a mean of 72.5 days                        [2,7,9-11,13,16,19,22,24,25] . These studies included patients with

                          varying ages, frailty, and comorbidities, so the wide range in length of stay is not necessarily reflective of the Meek itself.



                          Several papers have evaluated postoperative infection rates in Meek patients in comparison to those receiving meshed grafts. Although infection has been cited
                                                                                                                                                                              [2,6]
                          as a cause of graft failure,  [1,32,33]  no statistically significant difference was found between the infection rates of the two cohorts . The same was true for the rate
                                            [24]
                          of colonization . In our experience, we have not observed a significantly elevated infection rate in patients receiving Meek grafts. However, data on this were
                          not specifically collected as part of this series, and this represents an area for future focus. This opinion is shared by other researchers, including those
                          conducting the ongoing intrapatient Meek RCT, who have listed postoperative infection rates in their outcomes for evaluation                         [8,34] .
   25   26   27   28   29   30   31   32   33   34   35