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Page 6 of 13 Wilson et al. Plast Aesthet Res. 2025;12:8 https://dx.doi.org/10.20517/2347-9264.2024.135

Table 1. Summary of comorbidities of < 20% TBSA (Series B) patient cohort
Total Significant cardiac, respiratory,
Patient Diabetes Malignancy Other
comorbidities kidney disease (CKD 3b/4/5)
1 1 N N N Spinal injury
2 3 N N N Chronic kidney disease, hypertension, cataracts
3 0 N N N n
4 1 N N N HTN
5 5 Y N N Diabetic neuropathy, cataracts, HTN,
hyperlipidemia
6 3 N Y N Hypertension, stroke
7 1 N N N arthritis
8 0 N N N n
9 8 Y N MI, HFREF Cataracts, hypertension, chronic kidney disease,
peripheral neuropathy
10 1 N N N stroke
11 3 Y N N Hypercholesterolemia, hypertension
12 - - - - -
13 - - - - -
14 4 Y N MI Chronic kidney disease, benign prostatic
hyperplasia, hypercholesterolemia, hypertension
15 7 Y N N Chronic kidney disease, benign prostatic
hyperplasia, hypercholesterolemia, hypertension
16 4 Y N MI, HFREF Hypercholesterolemia
17 3 Y N MI Barrett’s esophagus, pancreatitis, benign
prostatic hyperplasia
18 6 Y N MI, HFREF Tension headaches, visual impairment,
hypertension
19 3 N N N Bipolar, hypertension, hypothyroidism
20 1 N N N depression
21 - - - - -
23 1 N N N HTN
24 0 N N N n
25 5 N N MI Cyclical vomiting, anxiety, depression,
hypertension
26 1 N N N Mental health disorder
27 4 N N N Atrial fibrillation, dementia, hypertension,
osteoporosis
TBSA: Total body surface area; CKD: chronic kidney disease; HTN: hypertension; MI: myocardial infarction; HFREF: heart failure with reduced
ejection fraction.

greater contractility of thicker split skin grafts [29,30] . A key advantage of Meek is its ability to provide a precise
calculation of the TBSA that can be covered by a donor site of a given size. For instance, a 20 cm × 20 cm
donor site expanded at a 1:4 ratio can cover a 40 cm × 40 cm wound bed.

One potential drawback of Meek is the surgical time required. This paper does not specifically assess
operative duration, while data from a previous series at our center demonstrated that the Meek technique,
on average, required 17 min less than conventional meshed grafting in comparable patients with similar
wound sizes. Additionally, published literature supports the observation that Meek grafting can reduce
[1]
operative time. [7,31] We acknowledge that there is a learning curve associated with this technique and that, in
addition to this, its success depends on appropriate planning and staffing. We believe the reduced surgical
time in our series is largely due to an optimized workflow: by harvesting the donor site at the beginning of
the procedure, the primary surgeon can debride the burn wound while a trained colleague performs the