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Guo et al.                                                                                                                                                                                   The distribution of hair in Chinese

           INTRODUCTION                                       3 × n 3  + 4 × n 4  + 5 × n 5 .
           Follicular unit transplantation (FUT) and follicular unit   As the vertex and temporal regions of most AGA
           extraction (FUE) have become two preferred methods   patients had no hair, these regions had no statistical
           in hair transplantation surgery due to their aesthetic   meaning. Thus, the photography and statistical
           and natural postoperative appearance, and high     methods were only applied to the occipital region in this
           survival rate. FUT and FUE achieve their cosmetic and   group [Figure 2]. The statistical data were processed
           modification effects by the redistribution of existing   in the same way as in the healthy group.
           hair rather than by increasing the absolute number
           of hairs. Thus, no matter which surgery method to   Statistical analysis
           choose, patients will require detailed evaluation in
           multiple aspects, including the area of donor site to   SPSS 13.0 software was used for statistical analysis
           excise or extract [1,2] . Western scholars have conducted   of the data. The measurement data were expressed
           detailed research on the hair distribution of whites   as mean ± standard deviation. Comparisons between
           and Africans [3-5] . These studies have shown that the   two  groups  were  performed  using  independent-
           hair density of Asians is lower than that of whites and   samples t-tests. Comparisons among multiple groups,
           Africans. However, due to geographical and ethnic   such as homogeneity of variance, were performed
           differences leading to disparities in hair distribution   using one-way analysis of variance (ANOVA) and
           among Asians, it is necessary to investigate the   Bonferroni pairwise comparison. Welch’s approximate
           hair distribution in Han Chinese. This paper aims to
           explore the normal hair distribution characteristics of
           Han Chinese, in order to facilitate clinical practice.

           METHODS

           Research subjects
           A total of 146 healthy volunteers were Han Chinese
           residents aged 20-70 years. None had ever received
           hair coloring, perming, or other treatments. The
           volunteers and their relatives had no hair diseases,
           such as androgenetic alopecia, alopecia areata, or
           hirsutism. Another 41 patients with androgenetic
           alopecia  (AGA)  were  selected  for  comparative
           analysis. All volunteers were informed of the
           objectives and specific methods of the study, and all                      2
           gave informed consent.                             Figure 1: Area measured at 1 cm . The FU density in the occipital
                                                                                           2
                                                              region of healthy patient was 95 units/cm . FU: follicular unit
           Experimental method
           The vertex region (the intersection between the
           preauricular line connecting the left and right ears,
           and the line connecting the glabella and external
           occipital protuberance), temporal region (2 cm above
           the preauricular line for both ears), and occipital region
           (centered on the external occipital protuberance)
           in the volunteers were selected as the observation
           sites. Close-up photographs were taken of 2.5 cm ×
           1.5 cm areas within the observation regions after the
           hair within the area was trimmed. Photoshop CS5
           was used to read the images and count the number
           of follicular unit (FU) types (n 1 , n 2 , n 3 , n 4 , and n 5 )
           comprising of 1, 2, 3, 4 and 5 hairs, respectively,
                      2
           within 1 cm  of the photographed region [Figure 1].
           The following two formulas were use to calculate FU                        2
                                                    2
           density and hair density: FU density (hairs/cm ) = n 1  +   Figure 2: Area measured at 1 cm . The FU density in the occipital
                                                                                             2
                                                              region of AGA patient was 86 units/cm . AGA: androgenetic
                                             2
           n 2  + n 3  + n 4  + n 5 ;   Hair density (hairs/cm ) = n 1  + 2 × n 2  +   alopecia; FU: follicular unit
                           Plastic and Aesthetic Research ¦ Volume 4 ¦ September 28, 2017                 151
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