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Page 12 of 14            Guiotto et al. Plast Aesthet Res 2023;10:26  https://dx.doi.org/10.20517/2347-9264.2023.15























                                      Figure 6. Surgical treatment algorithm according to our experience.

               the extra limitations. Further clinical studies with a prospective design with larger cohorts, standardised
               quantification of GL and prolonged follow-up are advocated; all these will help to clarify therapeutical
               protocols and improve patient outcomes.

               In conclusion, for GL stage I and mild presentations, we suggest maximal conservative therapy at the first
               step. In stages II and above or in the presence of persisting clinical symptoms, physiological surgery should
               be proposed. Microsurgical options should be recommended in recurrent symptomatic GL (particularly
               when lymphorrhea/chylorrhea and/or recurrent perineal infections dramatically impact patient quality of
               life) and eventually combined with debulking.

               Alternatively, in the case of chronic and extended GL stage IIb-III, excisional procedures represent our first
               approach, considering the fibrotic and adipose tissue and the main component to address to reduce
               anatomical deformity and functional impairments [Figure 6]. Finally, we always recommend postoperative
               CDT to all patients, in order to maintain results and prevent recurrences.


               DECLARATIONS
               Authors’ contributions
               Authors who performed the surgeries: di Summa PG, Campisi C, Maruccia M
               Designed the study and participated in data analysis: di Summa PG
               Performed data analysis, interpretation, and manuscript preparation: Guiotto M
               Performed data acquisition, as well as provided administrative, technical, and material support: Elia R,
               Molinari L, Fresa M, Nicod Lalonde M

               Availability of data and materials
               The datasets used and/or analyzed during the current study are available from the corresponding author
               upon reasonable request and deposited at the University of Lausanne. All figures and tables are original.


               Financial support and sponsorship
               None.


               Conflicts of interest
               All authors declared that there are no conflicts of interest.
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