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García Nores et al. Plast Aesthet Res 2023;10:33                            Plastic and
               DOI: 10.20517/2347-9264.2022.146
                                                                                Aesthetic Research




               Review                                                                        Open Access



               Strategies for prevention and management of partial
               flap loss or fat necrosis in microvascular autologous

               breast reconstruction


               Gabriela D García Nores, Angela Cheng
               Department of Surgery, Division of Plastic and Reconstructive Surgery, Emory University, Atlanta, GA 30322, USA.

               Correspondence to: Dr. Angela Cheng, Department of Surgery, Division of Plastic and Reconstructive Surgery, Emory University,
               1364C Clifton Rd NE, Atlanta, GA 30322, USA. E-mail: angelacheng@emory.edu

               How to cite this article: García Nores GD, Cheng A. Strategies for prevention and management of partial flap loss or fat necrosis
               in microvascular autologous breast reconstruction. Plast Aesthet Res 2023;10:33. https://dx.doi.org/10.20517/2347-
               9264.2022.146

               Received: 15 Dec 2022  Revised: 20 Jun 2023  Accepted: 27 Jun 2023  Published: 30 Jun 2023

               Academic Editor: Gordon Kwanlyp Lee  Copy Editor: Yanbing Bai  Production Editor: Yanbing Bai

               Abstract
               Partial flap loss (skin involved) or fat necrosis following autologous breast reconstruction remains a dreaded
               postoperative complication despite significant advances in microsurgical techniques. Several strategies have been
               proposed in the preoperative and intraoperative period to prevent this complication ranging from preoperative
               imaging, intra-operative tissue perfusion assessment, appropriate perforator selection (location and number),
               maximizing inflow and outflow with additional anastomoses and/or pedicles, and minimizing ischemia time.
               Postoperative management of partial flap loss (when there is skin involvement) and fat necrosis remains a
               challenge, with very little published data focusing on classification, timing, and techniques. Early intervention
               versus close observation may depend on multiple patient factors and the degree or volume of necrosis. Secondary
               intervention options include hyperbaric oxygen therapy, fat aeration with a needle, liposuction, fat grafting, addition
               of another flap or implant, depending on the nature of the defect. This review summarizes the current evidence for
               each of these strategies to help the current surgeon understand their options in preventing and managing patients
               suffering from partial flap loss.

               Keywords: Partial flap loss, fat necrosis, prevention of fat necrosis










                           © The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0
                           International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
                           adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
               long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
               indicate if changes were made.

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