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Page 28 of 32                 Noor et al. Neuroimmunol Neuroinflammation 2019;6:10  I  http://dx.doi.org/10.20517/2347-8659.2019.18

               Experimental design, performed behavioral assessment and data analysis for hindpaw responses, RNA
               extractions and aided with manuscript preparation: Sun MS
               Tissue collection, aided with for behavioral assessment, small tissue RNA extraction, and generated PCR
               data: Vanderwall AG
               Performed behavioral assessments and extracted RNA from DRG tissues: Havard MA, Sanchez JE, Harris
               NW
               Provided resources and performed intravenous injection of BIRT377: Nysus MV, Norenberg JP
               Gifted some batches of BIRT377 and provided guidance about BIRT377 usage: Wagner CR, West HT
               Provided equipment, critical guidance and training for MSD immunoassays data analysis, and manuscript
               preparation: Jantzie LL
               Provided equipment and critical guidance for quantitative real-time PCR with Taqman probes: Mellios N
               Designed the studies, performed tissue dissection, reviewed data analysis, provided data interpretation and
               manuscript preparation: Milligan ED

               Availability of data and materials
               All data generated and analyzed for the current report is included within the article.

               Financial support and sponsorship
               This study was funded by the National Institutes of Alcoholism and Alcohol Abuse (NIAAA) (R21-
               AA023051), (R01-AA025967), (T32-AA014127), (P50-AA022534), and the National Institutes of Drug Abuse
               (NIDA) (DA018156), by the dedicated Health Research funds from the UNM SOM, and Research Funds
               from the UNM SOM Dept. of Anesthesiology & Critical Care Medicine.

               Conflicts of interest
               All authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               All procedures were approved by the Institutional Animal Care and Use Committee (IACUC) of The
               University of New Mexico Health Sciences Center, and closely adhered to guidelines from the International
               Association for the Study of Pain for the use of animals in research.

               Consent for publication
               Not applicable.

               Copyright
               © The Author(s) 2019.


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