Page 69 - Read Online
P. 69
Page 16 of 23 Poznyak et al. Microbiome Res Rep. 2026;5:3
16. Jiao Y, Wu L, Huntington ND, Zhang X. Crosstalk between gut microbiota and innate immunity and its implication in autoimmune
diseases. Front Immunol. 2020;11:282. DOI PubMed PMC
17. De Luca F, Shoenfeld Y. The microbiome in autoimmune diseases. Clin Exp Immunol. 2019;195:74-85. DOI PubMed PMC
18. Lin L, Zhang K, Xiong Q, et al. Gut microbiota in pre-clinical rheumatoid arthritis: From pathogenesis to preventing progression. J
Autoimmun. 2023;141:103001. DOI
19. Fan J, Jiang T, He D. Advances in the implications of the gut microbiota on the treatment efficacy of disease-modifying anti-rheumatic
drugs in rheumatoid arthritis. Front Immunol. 2023;14:1189036. DOI PubMed PMC
20. Wells PM, Williams FMK, Matey-Hernandez ML, Menni C, Steves CJ. 'RA and the microbiome: do host genetic factors provide the
link? J Autoimmun 2019;99:104-15. DOI PubMed PMC
21. Malczewski AB, Coward JI, Ketheesan N, Navarro S. Immunometabolism: the role of gut-derived microbial metabolites in optimising
immune response during checkpoint inhibitor therapy. Clin Transl Med. 2025;15:e70472. DOI PubMed PMC
22. Romero-Figueroa MDS, Ramírez-Durán N, Montiel-Jarquín AJ, Horta-Baas G. Gut-joint axis: gut dysbiosis can contribute to the onset
of rheumatoid arthritis via multiple pathways. Front Cell Infect Microbiol. 2023;13:1092118. DOI PubMed PMC
23. Longo UG, Lalli A, Bandini B, et al. Role of the gut microbiota in osteoarthritis, rheumatoid arthritis, and spondylarthritis: an update on
the gut-joint axis. Int J Mol Sci. 2024;25:3242. DOI PubMed PMC
24. Arya P, Sharma V, Singh P, Thapliyal S, Sharma M. Bacterial endotoxin-lipopolysaccharide role in inflammatory diseases: an overview.
Iran J Basic Med Sci. 2025;28:553-64. DOI PubMed PMC
25. Farhana A, Khan YS. Biochemistry, Lipopolysaccharide. [Updated 2023 Apr 17]. In: StatPearls [Internet]. Treasure Island (FL):
StatPearls Publishing; 2024 Jan-. Available online: https://www.ncbi.nlm.nih.gov/books/NBK554414/. [Last accessed 24 February
2026].
26. An L, Wirth U, Koch D, et al. The Role of Gut-derived lipopolysaccharides and the intestinal barrier in fatty liver diseases. J
Gastrointest Surg. 2022;26:671-83. DOI PubMed PMC
27. Lin TL, Shu CC, Chen YM, et al. Like cures like: pharmacological activity of anti-inflammatory lipopolysaccharides from gut
microbiome. Front Pharmacol. 2020;11:554. DOI PubMed PMC
28. Mahroum N, Seida R, Shoenfeld Y. Triggers and regulation: the gut microbiome in rheumatoid arthritis. Expert Rev Clin Immunol.
2023;19:1449-56. DOI PubMed
29. Reyes-Castillo Z, Valdés-Miramontes E, Llamas-Covarrubias M, Muñoz-Valle JF. Troublesome friends within us: the role of gut
microbiota on rheumatoid arthritis etiopathogenesis and its clinical and therapeutic relevance. Clin Exp Med. 2021;21:1-13. DOI
PubMed
30. Balasundaram D, Veerasamy V, Sylvia Singarayar M, Neethirajan V, Ananth Devanesan A, Thilagar S. Therapeutic potential of
probiotics in gut microbial homeostasis and Rheumatoid arthritis. Int Immunopharmacol. 2024;137:112501. DOI PubMed
31. Greenblatt HK, Kim HA, Bettner LF, Deane KD. Preclinical rheumatoid arthritis and rheumatoid arthritis prevention. Curr Opin
Rheumatol. 2020;32:289-96. DOI PubMed PMC
32. Romão VC, Fonseca JE. Disease mechanisms in preclinical rheumatoid arthritis: a narrative review. Front Med (Lausanne).
2022;9:689711. DOI PubMed PMC
33. Cope AP, Jasenecova M, Vasconcelos JC, et al.; APIPPRA study investigators. Abatacept in individuals at high risk of rheumatoid
arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial. Lancet.
2024;403:838-49. DOI PubMed PMC
34. Tsetseri MN, Silman AJ, Keene DJ, Dakin SG. The role of the microbiome in rheumatoid arthritis: a review. Rheumatol Adv Pract.
2023;7:rkad034. DOI PubMed PMC
35. Coradduzza D, Bo M, Congiargiu A, et al. Decoding the microbiome’s influence on rheumatoid arthritis. Microorganisms.
2023;11:2170. DOI PubMed PMC
36. Alpízar-Rodríguez D, Finckh A, Gilbert B. The role of nutritional factors and intestinal microbiota in rheumatoid arthritis development.
Nutrients. 2020;13:96. DOI PubMed PMC
37. Nii T, Maeda Y, Motooka D, et al. Genomic repertoires linked with pathogenic potency of arthritogenic Prevotella copri isolated from
the gut of patients with rheumatoid arthritis. Ann Rheum Dis. 2023;82:621-9. DOI PubMed PMC
38. Rooney CM, Mankia K, Emery P. The role of the microbiome in driving RA-related autoimmunity. Front Cell Dev Biol. 2020;8:538130.
DOI PubMed PMC
39. Poznyak AV, Kashirskikh DA, Postnov AY, Popov MA, Sukhorukov VN, Orekhov AN. Sialic acid as the potential link between lipid
metabolism and inflammation in the pathogenesis of atherosclerosis. Braz J Med Biol Res. 2023;56:e12972. DOI
40. Maeda Y, Takeda K. Host-microbiota interactions in rheumatoid arthritis. Exp Mol Med. 2019;51:1-6. DOI PubMed PMC
41. Koh JH, Lee EH, Cha KH, Pan CH, Kim D, Kim WU. Factors associated with the composition of the gut microbiome in patients with
established rheumatoid arthritis and its value for predicting treatment responses. Arthritis Res Ther. 2023;25:32. DOI PubMed PMC
