Page 39 - Read Online

Geerlings et al. Microbiome Res Rep 2024;3:36 https://dx.doi.org/10.20517/mrr.2024.06 Page 15 of 15

diss=y. [Last accessed on 13 Jun 2024].
29. Chang Y, Yang Y, Xu N, Mu H, Zhang H, Duan J. Improved viability of Akkermansia muciniphila by encapsulation in spray dried
succinate-grafted alginate doped with epigallocatechin-3-gallate. Int J Biol Macromol 2020;159:373-82. DOI PubMed
30. Marcial-Coba MS, Cieplak T, Cahú TB, Blennow A, Knøchel S, Nielsen DS. Viability of microencapsulated Akkermansia muciniphila
and Lactobacillus plantarum during freeze-drying, storage and in vitro simulated upper gastrointestinal tract passage. Food Funct
2018;9:5868-79. DOI PubMed
31. Marcial-Coba MS, Saaby L, Knøchel S, Nielsen DS. Dark chocolate as a stable carrier of microencapsulated Akkermansia muciniphila
and Lactobacillus casei. FEMS Microbiol Lett 2019;366:fny290. DOI PubMed
32. Ouwerkerk JP, van der Ark KCH, Davids M, et al. Adaptation of Akkermansia muciniphila to the oxic-anoxic interface of the mucus
layer. Appl Environ Microbiol 2016;82:6983-93. DOI PubMed PMC
33. Hagi T, Geerlings SY, Nijsse B, Belzer C. The effect of bile acids on the growth and global gene expression profiles in Akkermansia
muciniphila. Appl Microbiol Biotechnol 2020;104:10641-53. DOI PubMed PMC
34. Ottman N, Huuskonen L, Reunanen J, et al. Characterization of outer membrane proteome of Akkermansia muciniphila reveals sets of
novel proteins exposed to the human intestine. Front Microbiol 2016;7:1157. DOI PubMed PMC
35. Ottman N, Reunanen J, Meijerink M, et al. Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut
barrier function. PLoS One 2017;12:e0173004. DOI PubMed PMC
36. Yoon HS, Cho CH, Yun MS, et al. Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves
glucose homeostasis and ameliorates metabolic disease in mice. Nat Microbiol 2021;6:563-73. DOI PubMed
37. Meng X, Zhang J, Wu H, Yu D, Fang X. Akkermansia muciniphila Aspartic Protease Amuc_1434* inhibits human colorectal cancer
LS174T cell viability via TRAIL-mediated apoptosis pathway. Int J Mol Sci 2020;21:3385. DOI PubMed PMC
38. Qian K, Chen S, Wang J, Sheng K, Wang Y, Zhang M. A β-N-acetylhexosaminidase Amuc_2109 from Akkermansia muciniphila
protects against dextran sulfate sodium-induced colitis in mice by enhancing intestinal barrier and modulating gut microbiota. Food
Funct 2022;13:2216-27. DOI PubMed
39. Segers A, de Vos WM. Mode of action of Akkermansia muciniphila in the intestinal dialogue: role of extracellular proteins,
metabolites and cell envelope components. Microbiome Res Rep 2023;2:6. DOI PubMed PMC
40. Druart C, Plovier H, Van Hul M, et al. Toxicological safety evaluation of pasteurized Akkermansia muciniphila. J Appl Toxicol
2021;41:276-90. DOI PubMed PMC
41. Turck D, Bohn T, Castenmiller J, et al; EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA). Safety of pasteurised
Akkermansia muciniphila as a novel food pursuant to Regulation (EU) 2015/2283. EFSA J 2021;19:e06780. DOI PubMed PMC
42. Geerlings SY. A rising star: a comprehensive approach to Akkermansia muciniphila ecosystems, interactions and applications. 2023.
Available from: https://research.wur.nl/en/publications/a-rising-star-a-comprehensive-approach-to-akkermansia-muciniphila. [Last
accessed on 13 Jun 2024].
43. Plugge CM. Anoxic media design, preparation, and considerations. Methods Enzymol 2005;397:3-16. DOI PubMed
44. Shetty SA, Kostopoulos I, Geerlings SY, Smidt H, de Vos WM, Belzer C. Dynamic metabolic interactions and trophic roles of human
gut microbes identified using a minimal microbiome exhibiting ecological properties. ISME J 2022;16:2144-59. DOI PubMed PMC
45. Chakraborty S, Gogoi M, Chakravortty D. Lactoylglutathione lyase, a critical enzyme in methylglyoxal detoxification, contributes to
survival of Salmonella in the nutrient rich environment. Virulence 2015;6:50-65. DOI PubMed PMC
46. Guthrie B, Wickner W. Trigger factor depletion or overproduction causes defective cell division but does not block protein export. J
Bacteriol 1990;172:5555-62. DOI PubMed PMC
47. Wang J, Xu W, Wang R, Cheng R, Tang Z, Zhang M. The outer membrane protein Amuc_1100 of Akkermansia muciniphila promotes
intestinal 5-HT biosynthesis and extracellular availability through TLR2 signalling. Food Funct 2021;12:3597-610. DOI PubMed
48. Hudek L, Premachandra D, Webster WA, Bräu L. Role of phosphate transport system component PstB1 in phosphate internalization
by Nostoc punctiforme. Appl Environ Microbiol 2016;82:6344-56. DOI PubMed PMC
49. den Besten HM, Arvind A, Gaballo HM, Moezelaar R, Zwietering MH, Abee T. Short- and long-term biomarkers for bacterial
robustness: a framework for quantifying correlations between cellular indicators and adaptive behavior. PLoS One 2010;5:e13746.
DOI PubMed PMC
50. Nguyen PT, Nguyen TT, Bui DC, Hong PT, Hoang QK, Nguyen HT. Exopolysaccharide production by lactic acid bacteria: the
manipulation of environmental stresses for industrial applications. AIMS Microbiol 2020;6:451-69. DOI PubMed PMC