Page 53 - Read Online

Page 6 of 11 Silvestri et al. Mini-invasive Surg 2019;3:5 I http://dx.doi.org/10.20517/2574-1225.2018.67

Table 1. Contemporary comparative series comparing radiofrequency with partial nephrectomy and/or radical nephrectomy
with oncological outcomes
Therapy Number of Study Follow up
Author Year End point Outcomes
patients design (months)
Arnoux et al. [43] 2013 Survival, recurrence, RFA 36 Prospective 22 No recurrences in RFA and
complications PN 14 22 PN
No other oncological
outcomes
Bensalah et al. [44] 2007 Survival, recurrence, RFA 46 Retrospective Mean 15 97% RFS, 100% CSS
complications PN 56
Bird et al. [45] 2009 Survival, recurrence, RFA 36 Retrospective 12 No recurrences
complications, renal PN 33 27 No deaths
function

Chang et al. [46] 2015 Survival, recurrence, RFA 53 Retrospective 68 No recurrences
complications, renal PN 53 69 No deaths
function
Chang et al. [47] 2015 Survival, recurrence, RFA 64 Retrospective 66 85.5%, 92.6%, 81.0%
complications, renal PN 57 70 (OS, CSS, DFS)
function 5-year 96.6%, 96.6%, 89.7%
outcome (OS, CSS, DFS)
Ji et al. [48] 2016 Recurrence, RFA 105 Retrospective 78 93.3%, 98.0%, 97.1%
complications PN 74 82 (OS, CSS, DFS)
5-year 94.6%, 98.5%, 97.3%
outcome (OS, CSS, DFS)
Kim et al. [49] 2015 Survival, recurrence, RFA 27 Retrospective 17 1 recurrence
complications, PN 27 11 2 recurrence
renal function
Liu et al. [50] 2017 Survival, recurrence, RFA 93 Prospective 78 84.9%, 82.8% (OS, DFS)
complications, PN 120 database 88.3%, 88.8% (OS, DFS)
renal function Differences > in lesions
> 4 cm
Lucas et al. [51] 2008 Recurrence, RFA 86 Retrospective 40 6 recurrence
renal function PN 85 44 2 recurrence
RN 71 26 0 recurrence
Olweny et al. [52] 2012 Recurrence RFA 37 Prospective 78 97.2%, 89.2%, 97%, 91.7%
PN 37 73 (OS, DFS, CSS, local RFS)
5-year 100%, 89.2%, 100%, 94.6%
(OS, DFS, CSS, local RFS)
Pantelidou et 2016 Recurrence RFA 63 Retrospective 48 6 Local recurrence, 3 Met
al. [53] PN (robotic) 63 18 1 Local Recurrence, 1 Met
DFS was not significantly
different between the two
groups (HR = 0.84, 95%Cl:
0.19-3.4; P = 0.80
Raman et al. [54] 2010 Recurrence, renal RFA 47 Retrospective 18 5 recurrence
function PN 42 30 3 recurrence
Stern et al. [55] 2007 Recurrence, RFA 40 Retrospective - 2 recurrence, 93.4% (DFS)
complications PN 37 1 recurrence, 95.8% (DFS)
Sung et al. [56] 2012 Recurrence, RFA 40 Prospective 37 94.7% (RFS)
complications, PN 110 37 98.9% (RFS)
renal function 3-year
Takaki et al. [57] 2010 Recurrence, RFA 51 Retrospective 34 75.0%, 100%, 98.0%
complications, PN 10 26 (OS, RCC-rS, DFS)
renal function RN 40 100%, 100%, 75.0%
5-year (OS, RCC-rS, DFS)
100%, 100%, 95.0%
(OS, RCC-rS, DFS)
RFA: radiofrequency; PN: partial nephrectomy; RN: radical nephrectomy; OS: overall survival; CSS: cancer-specific survival; DFS: disease-
free survival; RFS: recurrence-free survival; RCC: renal cell carcinoma; RCC-rS: renal cell carcinoma-related survival

was found between LCA and PCA in renal function outcomes in the two largest comparative studies
published so far [29-31] .

[30]
The reported overall rates of complications for CA procedures range from 7.8% to 20% . The overall
published complication rates for PCA (7.8%-12.9%) were lower than the rates for LCA (15%-20%) [30,32] .