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Silvestri et al. Mini-invasive Surg 2019;3:5                   Mini-invasive Surgery
               DOI: 10.20517/2574-1225.2018.67




               Review                                                                        Open Access


               Laparoscopic ablative techniques

               Tommaso Silvestri, Bernardino de Concilio, Guglielmo Zeccolini, Antonio Celia

               Urology Unit, “San Bassiano” Hospital, ULSS7 Pedemontana, Bassano del Grappa, VI 36061, Italy.

               Correspondence to: Dr. Tommaso Silvestri, Urology Unit, “San Bassiano” Hospital, ULSS7 Pedemontana, Bassano del Grappa,
               VI 36061, Italy. E-mail: tommaso.silve@gmail.com

               How to cite this article: Silvestri T, de Concilio B, Zeccolini G, Celia A. Laparoscopic ablative techniques. Mini-invasive Surg
               2019;3:5. http://dx.doi.org/10.20517/2574-1225.2018.67
               Received: 30 Nov 2018    First Decision: 30 Nov 2018    Revised: 28 Jan 2019   Accepted: 11 Feb 2019    Published: 4 Mar 2019

               Science Editor: Richard Lawrence John Naspro    Copy Editor: Cui Yu    Production Editor: Huan-Liang Wu



               Abstract
               Ablative techniques (AT) offer a combination of nephron-sparing and minimally invasive approaches. AT include
               different options and cryoablation (CA) and radiofrequency ablation (RFA) have been relatively safe and traditionally can
               be either performed laparoscopically or percutaneously. CA and RFA have emerged as a leading option for renal ablation,
               and compared with surgical techniques they offer benefits in preserving renal function with fewer complications, shorter
               hospitalization times, and allow for quicker convalescence. A mature dataset exists at this time, with intermediate and
               long-term follow up data available. Generally, laparoscopic access was the first technique used in the past, and typically
               for anterior and lateral mass. Afterwards, with the improvements in imaging and percutaneous techniques, laparoscopic
               approaches are progressively decreased and currently limited in few lesions and in relation with the surgeon’s and
               center’s experience. Nevertheless, laparoscopic CA and RFA could be useful techniques and currently, recommendations
               as a first-line therapy are made at this time in limited populations, including elderly patients, patients with multiple
               comorbidities, and those with imperative indications of a nephron sparing surgery. As more data emerge on oncologic
               efficacy, and technical experience continue to improve, the application of AT will likely be extended in future treatment
               guidelines and laparoscopic approaches will be a valid option in the era of tailored therapy.


               Keywords: Laparoscopic kidney cryoablation, small renal masses, laparoscopic ablative techniques




               INTRODUCTION
               Although surgery remains the definitive recommended treatment of small renal masses (SRM), ablative
               techniques (AT) have emerged recently, particularly for tumors < 4 cm, and for those patients who
               cannot undergo surgery or with imperative indications of nephron sparing surgery (NSS). AT included:
               cryoablation (CA), radiofrequency ablation (RFA), microwave ablation, laser thermal ablation, and high-
               intensity focused ultrasound. Historically CA and RFA have been introduced first worldwide, and recently

                           © The Author(s) 2019. Open Access This article is licensed under a Creative Commons Attribution 4.0
                           International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use,
                sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long
                as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license,
                and indicate if changes were made.


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