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Aslam et al. Mini-invasive Surg 2018;2:10  I  http://dx.doi.org/10.20517/2574-1225.2017.42                                            Page 5 of 7


               status. More patients in the control period had open operations and more had conversions from laparoscopic
               to open procedures that during the CO measurement period. Patients in the earlier period may have required
               more advanced care because of the higher level of invasiveness of the operation. These differences alone
               would explain a large percentage of the change in level 2/3 care required in the earlier period, and not the
               implementation of CO monitoring. Due to the lack of data about the precise decision for admission in ICU/
               HDU in the control group did not allow analysis for these co-founders. The authors did not notice a change
               in practice for the use of bowel preparation for colon surgery patients. No mechanical bowel preparation is
               used at the unit for right colonic surgery and only Phosphate enema is used for left sided colonic and rectal
               surgery. Enhanced recovery protocols have recommended the elimination of mechanical bowel preparation
               which would reduce IV volume support for patients undergoing colorectal surgery. Though practice for
               bowel preparation did not change in study period, a lack of data in the consistency in bowel preparation
               over the entire time of the study highlights the issue that even a minor change in practice combined with
               less invasive surgical procedures makes the postoperative care of the patients in the two periods of time very
               different.


               Intra-operative indices of tissue hypo-perfusion resulting in gastrointestinal dysfunction are the most
               common post-operative complications in patients undergoing moderate-to high risk emergency GI surgery.
               Intra-operative CO optimisation and GDFT for patients undergoing colorectal surgery reduces the post-
                                                                [9]
               operative morbidity, mortality and length of hospital stay . GDFT has also been shown to be cost effective
               in reducing hospital stays and the surgical complications [32,33] . It would be interesting to extend this study to
               use intra-operative cardiac output monitoring for patients undergoing emergency laparotomy and to assess
               the outcomes through the National Emergency Laparotomy Audit.

               In conclusion, the use of intra-operative cardiac monitoring does not significantly alter the immediate post-
               operative outcomes; however, it reduces the need for admission to level 2/3 care facilities post-operatively.
               Intra-operative cardiac output monitoring might become an effective way to reduce the need for higher
               level critical care beds in patients undergoing elective colorectal surgery. A larger cohort study is needed to
               further confirm these findings and account for any co-founders.


               DECLARATIONS
               Authors’ contributions
               Conception and design: Merchant J, Evans R, Ihedioha U, Kang P
               Acquisition of data: Aslam MI, Smith H, Akhtar N
               Analysis and interpretation of data: Aslam MI
               Article drafting: Aslam MI, Smith H, Akhtar N
               Revision for important intellectual content: Currow C, Merchant J, Evans R, Ihedioha U, Kang P
               Final approval: Aslam MI, Smith H, Currow C, Akhtar N, Merchant J, Evans R, Ihedioha U, Kang P


               Financial support and sponsorship
               None.


               Conflicts of interest
               There are no conflicts of interest.


               Patient consent
               No personal information for patients involved in the article.


               Ethics approval
               Ethics review was not required by the institution for a retrospective analysis for prospectively maintained
               database.
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