Page 38 - Read Online
P. 38

Priego et al. Mini-invasive Surg 2018;2:6  I  http://dx.doi.org/10.20517/2574-1225.2018.01                                            Page 5 of 7


               Table 1. Demographic characteristics of patients
                                             Case 1       Case 2                Case 3             Case 4
                Age (year)/gender    82/M            74/F               78/F            64/F
                ASA                  III             II                 II              III
                Comorbidities        COPD, DM        Hypertension       Hypertension, DM, DL  Hypertension, dilated
                                                                                        myocardiopathy,
                                                                                        ischemic cerebrovascular
                                                                                        accident
                Symptoms             Haematemesis    Haematemesis       Epigastric pain  Epigastric pain
                Diagnosis            Endoscopy,      Endoscopy,         Endoscopy,      Endoscopy,
                                     CT scan         Eco-endoscopy,     Eco-endoscopy,  Eco-endoscopy,
                                                     CT scan            CT scan,        CT scan
                                                                        Barium swallow
                                                                        MRI
                Hystopathology       GIST low malignancy,   GIST low malignancy, mitotic  Leiomyoma  Leiomyoma
                                     mitotic index < 5/50  index
                                                     < 5/50
                Size tumor (cm)      5.5             3                  3               2.3
                Operative time (min)  120            195                145             232
                Intraoperative complications  None   None               None            Methilene blue leakage
                Postoperative complications  None    None               None            Fever, haematemesis
                Oral intake (days)   3               2                  3               10
                Hospital stay (days)  7              4                  6               15
                Mortality            No              No                 No              No
               M: male; F: female; ASA: American Society of Anesthesiologists; COPD: chronic obstructive pulmonary disease; DM: diabetes mellitus;
               CT: computerized tomography; GIST: gastrointestinal stromal tumors; DL: dyslipemia; MRI: magnetic resonance imaging



               The mean operation time was 173 min (range 120-232 min). There were no conversions. There were no
               intraoperative complications, but in one of the patients, a methylene blue leakage was observed when
               suture was checked, which was reinforced. No postoperative complications were described, but patient
               with methylene blue leakage experimented hyperpyrexia in the first 24 h after operation and haematemesis.
               Both problems were treated conservatively.

               The mean postoperative stay was 8 days (range 4-15 days). There was no death in our series.

               At a mean follow-up of 31 months, all of our patients are asymptomatic and free of recurrence. None
               showed evidence of stenosis of the EGJ or acid reflux symptoms.


               DISCUSSION
               Laparoscopic wedge resection is widely accepted as a choice of treatment for GST, especially for tumors in
               the anterior wall, lesser curvature, and greater curvature. However, tumors on the posterior wall at the EGJ
                                       [1-5]
               remain difficult to approach .
                          [6]
               Privette et al.  proposed a tailored location-based standardized approach to resection of gastric GIST. This
               new classification on the basis of tumor location considers type 1 tumors located in fundus and greater
               curvature, type 2 for tumors in the antrum-prepyloric region and type 3 for tumors in the lesser curvature
               and EGJ. The surgical approach as dictated by tumor location would be a laparoscopic wedge resection for
               type 1, a laparoscopic distal gastrectomy for large type 2 tumors, and a laparoscopic transgastric resection
               for type 3.

               The optimal approach to GISTs located near EGJ is not well defined. Such tumors have been reported as
                                                                                                      [7]
               the reason for conversion, planned open procedure, and exclusion indication for laparoscopic approach .

               Several laparoscopic approaches have been described for the surgical treatment of gastric GIST near the
   33   34   35   36   37   38   39   40   41   42   43