Page 41 - Read Online
P. 41

Bongiolatti et al. Mini-invasive Surg 2020;4:41  I  http://dx.doi.org/10.20517/2574-1225.2020.28                                   Page 9 of 11

               undesirable, but competitors are now present on the market and could improve developments, diffusion of
               ideas and decreasing the costs of robot-assisted surgery.


               In conclusion, although possible with a minimally-invasive approach, trans-thoracic esophagectomy is
               still associated with significant post-operative complications. It has demonstrated acceptable oncological
               outcomes in terms of radicality, lymph node dissection, overall and disease-free survival. The robotic
               platform has shown some advantages in lymph node dissection, nerve sparing, improved intra-thoracic
               anastomosis and faster recovery after surgery, but large studies are necessary to understand the actual role
               of RAMIE in the multimodal treatment of EC.


               DECLARATIONS
               Authors’ contributions
               Conceptualization:Bongiolatti S
               Data collection: Bongiolatti S, Farronato A
               Formal Analysis, investigation, methodology, project administration, resources and software: Bongiolatti S
               Supervision: Bongiolatti S, Voltolini L
               Validation and visualization: all authors
               Writing-original draft and writing-review and editing: Bongiolatti S

               Availability of data and materials
               Not applicable.

               Financial support and sponsorship
               None.

               Conflicts of interest
               All authors declared that there are no conflicts of interest.

               Ethical approval and consent to participate
               Not applicable.


               Consent for publication
               Not applicable.

               Copyright
               © The Author(s) 2020.


               REFERENCES
                                                              ®
               1.   NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines ) Esophageal and Esophagogastric Junction Cancers. Version 4.2019
                   - December 20, 2019 NCCN.org https://www.nccn.org
               2.   Lordick F, Mariette C, Haustermans K, Obermannová R, Arnold D; ESMO Guidelines Committee. Oesophageal cancer: ESMO Clinical
                   Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2016;27:v50-7.
               3.   Cunningham D, Allum WH, Stenning SP, Thompson JN, Van de Velde CJ, et al. Perioperative chemotherapy versus surgery alone for
                   resectable gastroesophageal cancer. N Engl J Med 2006;355:11-20.
               4.   Cooper JS, Guo MD, Herskovic A, Macdonald JS, Martenson Jr JA, et al. Chemoradiotherapy of locally advanced esophageal cancer:
                   long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group. JAMA 1999;281:1623-7.
               5.   Enzinger PC, Mayer RJ. Esophageal cancer. N Engl J Med 2003;349:2241-52.
               6.   Safranek PM, Cubitt J, Booth MI, Dehn TC. Review of open and minimal access approaches to oesophagectomy for cancer. Br J Surg
                   2010;97:1845-53.
               7.   Straatman J, Van Der Wielen N, Cuesta MA, Daams F, Garcia JR, et al. Minimally invasive versus open esophageal resection: three-year
                   follow-up of the previously reported randomized controlled trial: the TIME trial. Ann Surg 2017;266:232-6.
   36   37   38   39   40   41   42   43   44   45   46