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Nota et al. Mini-invasive Surg 2020;4:74  I  http://dx.doi.org/10.20517/2574-1225.2020.57                                        Page 5 of 9

               Table 2. Operative characteristics and histopathological outcomes
                Parameter                                                              Outcome
                Resections performed, n (%)
                 Minor resection solely including anterolateral segments               32 (46)
                    Wedge resection                                                    17 (24)
                    Segmental resection                                                15 (21)
                 Minor resection including posterosuperior segments                    28 (40)
                    Wedge resection                                                    21 (30)
                    Segmental resection                                                7 (10)
                 Major resection (right and left hepatectomy)                          10 (14)
                Surgical details
                 Concomitant procedures, n (%)                                         7 (10)
                                      1,
                 Operative time, mean (SD), min ^                                      160 (78)
                                     2,
                 Console time, mean (SD), min *                                        111 (69)
                                                3,
                 Parenchymal transection time, mean (SD), min *                        43 (26)
                 EBL, median (IQR), mL                                                 150 (40-300)
                    RBC transfusions, median (IQR)                                     0 (0-0)
                    FFP transfusions, median (IQR)                                     0 (0-0)
                 Conversion to laparotomy, n (%)                                       5 (7)
                 Placement of surgical drain, n (%)                                    27 (38)
                 Use of biological agents (TachoSil, Surgicel), n (%)*                 51 (79)
                 Pringle manoeuvre performed (intermittent clamping), n (%)            31 (44)
                 Duration of inflow occlusion, mean (SD) min   1                       41 (15)
                 Epidural analgesia, n (%)                                             20 (29)
                 Stapler loads used per procedure, median (IQR)*                       0 (0-2)
                 Robotic system used, n (%)
                    da Vinci Si surgical system                                        55 (79)
                    da Vinci X surgical system                                         6 (9)
                    da Vinci Xi surgical system                                        9 (13)
                Histopathological outcomes, n (%)
                 Definitive diagnosis
                    CRLM                                                               31 (44)
                    Metastases, other                                                  5 (7)
                    HCC                                                                15 (21)
                    Intrahepatic Cholangiocarcinoma                                    4 (6)
                    Benign                                                             13 (19)
                    Other                                                              2 (3)
                 Cirrhosis on final pathology, n (%)                                   8 (11)
                                #
                 Radical (R0) resection                                                42 (76)
                 Tumor size, mean (SD), mm &                                           37 (26)
                                             3
               1 One missing value;  four missing values;  twenty missing values; ^operative time for liver resection, corrected for concomitant
                              2
                                          #
                                                                &
               procedures; *converted cases excluded;  solely reported for malignancies;  in cases of multiple resected tumours, only the largest tumour
               was included in the calculation. SD: standard deviation; IQR: interquartile range; RBC: red blood cells; FFP: fresh frozen plasma; CRLM:
               colorectal liver metastases; HCC: hepatocellular carcinoma; EBL: estimated blood loss
               (n = 8), left or right hepatectomies (n = 8), resections of the posterior sector (n = 3), and resections of
               segment 7 or 8 (n = 3). Overall, median blood loss was 150 mL (IQR 40-300), and in 51 procedures (79%)
               biological agents were applied to the resection surface to ensure haemostasis and biliostasis when deemed
               appropriate. No technical errors or handling difficulties of the Vessel Sealer were encountered.

               Postoperative outcomes
               Postoperative outcomes are summarized in Table 3. Ten patients (14%) suffered from a major complication.
               Three patients (4%) suffered from bile leakage postoperatively, two of which underwent a left hepatectomy,
               and the third patient underwent a segmental resection of segment 5. Of the three patients who suffered
               from bile leakage, two patients needed additional radiological drainage. The median length of hospital stay
               was four days. In total, 37 patients (53%) were discharged on day 4 or earlier; 12 patients (17%) went home
               on postoperative day one or two.
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