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Pennestrì et al. Mini-invasive Surg. 2025;9:16 Mini-invasive Surgery
DOI: 10.20517/2574-1225.2025.03

Original Article Open Access

SADI-S: personal experience after 8 years

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Francesco Pennestrì 1,2,# , Livia Palmieri , Priscilla Francesca Procopio , Pierpaolo Gallucci , Antonio
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Laurino , Francesca Prioli , Francesco Greco , Luigi Ciccoritti , Piero Giustacchini , Annamaria Martullo ,
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Giulio Perrone , Luca Sessa , Giulia Salvi , Amerigo Iaconelli , Barbara Aquilanti , Giuseppe Marincola ,
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Caterina Guidone , Esmeralda Capristo , Geltrude Mingrone , Carmela De Crea , Marco Raffaelli 1,2
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UOC Chirurgia Endocrina e Metabolica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
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Centro di Ricerca in Chirurgia delle Ghiandole Endocrine e dell’Obesità, Università Cattolica del Sacro Cuore, Rome 00168, Italy.
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Ospedale Generale Madre Giuseppina Vannini Figlie di San Camillo, Roma 00177, Italy.
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Fondazione Istituto G. Giglio, Cefalù 90015, Italy.
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UniCamillus, Saint Camillus International University of Health and Medical Sciences, Rome 00131, Italy.
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UOSD Medicina Bariatrica, Fondazione Policlinico Universitario Agostinon Gemelli IRCCS, Rome 00168, Italy.
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UOC Chirurgia Generale e d’Urgenza e delle Nuove Tecnologie, Azienda Ospedaliera San Camillo Forlanini, Rome 00152, Italy.
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UOC Patologie dell’Obesità, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
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Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome 00168, Italy.
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Authors contributed equtally.
Correspondence to: Dr. Francesco Pennestrì, UOC Chirurgia Endocrina e Metabolica, Fondazione Policlinico Universitario
Agostino Gemelli IRCCS, Largo Agostino Gemelli, 8, Rome 00168, Italy. E-mail: francesco.pennestri@policlinicogemelli.it
How to cite this article: Pennestrì F, Palmieri L, Procopio PF, Gallucci P, Laurino A, Prioli F, Greco F, Ciccoritti L, Giustacchini P,
Martullo A, Perrone G, Sessa L, Salvi G, Iaconelli A, Aquilanti B, Marincola G, Guidone C, Capristo E, Mingrone G, De Crea C,
Raffaelli M. SADI-S: personal experience after 8 years. Mini-invasive Surg. 2025;9:16. https://dx.doi.org/10.20517/2574-1225.
2025.03
Received: 8 Jan 2025 First Decision: 21 Apr 2025 Revised: 23 Apr 2025 Accepted: 13 May 2025 Published: 20 May 2025
Academic Editor: Giulio Belli Copy Editor: Pei-Yun Wang Production Editor: Pei-Yun Wang
Abstract
Aim: Biliopancreatic diversion with duodenal switch (BPD-DS) was simplified by the single anastomosis duodeno-
ileal bypass with sleeve gastrectomy (SADI-S). It reduces the surgical duration and postoperative complications
while maintaining effectiveness in weight loss and mitigating comorbidities.
Methods: This study aims to report personal experiences regarding short- and medium-term outcomes 8 years
after the introduction of SADI-S in clinical practice and compare these with the current literature evidence.
Results: At our center, 4,854 bariatric procedures were executed from July 2016 to October 2024, with 157 (3.2%)
patients undergoing SADI-S/SADI. This included 104 (66.2%) primary SADI-Ss, 8 (5.1%) conversions to SADI-S,
and 45 (28.7%) SADI procedures. Conversion to SADI-S was planned in eight out of 157 after adjustable gastric
banding (6 cases) and Roux-en-Y gastric bypass (2 cases). Median age and preoperative body mass index (BMI)
© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution 4.0
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adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
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