Page 113 - Read Online
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Page 250 Mohammadi et al. J Transl Genet Genom 2020;4:238-50 I https://doi.org/10.20517/jtgg.2020.29
neuron network derived from human pluripotent stem cells. PLoS One 2017;12:e0178533.
67. Simkin D, Kiskinis E. Modeling pediatric epilepsy through iPSC-based technologies. Epilepsy Curr 2018;18:240-5.
68. Tidball AM, Neely MD, Chamberlin R, Aboud AA, Kumar KK, et al. Genomic instability associated with p53 knockdown in the
generation of huntington’s disease human induced pluripotent stem cells. PLoS One 2016;11:e0150372.
69. Mariani J, Coppola G, Zhang P, Abyzov A, Provini L, et al. FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation
in autism spectrum disorders. Cell 2015;162:375-90.
70. Bershteyn M, Nowakowski TJ, Pollen AA, Di Lullo E, Nene A, et al. Human iPSC-derived cerebral organoids model cellular features of
lissencephaly and reveal prolonged mitosis of outer radial glia. Cell Stem Cell 2017;20:435-49.e4.
71. Birey F, Andersen J, Makinson CD, Islam S, Wei W, et al. Assembly of functionally integrated human forebrain spheroids. Nature
2017;545:54-9.
72. Sloan SA, Andersen J, Pașca AM, Birey F, Pașca SP. Generation and assembly of human brain region-specific three-dimensional cultures.
Nat Protoc 2018;13:2062-85.
73. Lancaster MA, Renner M, Martin CA, Wenzel D, Bicknell LS, et al. Cerebral organoids model human brain development and
microcephaly. Nature 2013;501:373-9.
74. Krefft O, Jabali A, Iefremova V, Koch P, Ladewig J. Generation of Standardized and Reproducible Forebrain-type cerebral organoids
from human induced pluripotent stem cells. J Vis Exp 2018;131;56768.
75. Grebenyuk S, Ranga A. Engineering organoid vascularization. Front Bioeng Biotechnol 2019;7:39.
76. Sterlini B, Fruscione F, Baldassari S, Benfenati F, Zara F, et al. Progress of induced pluripotent stem cell technologies to understand
genetic epilepsy. Int J Mol Sci 2020;21:482.
77. Simonato M, French JA, Galanopoulou AS, O’Brien TJ. Issues for new antiepilepsy drug development. Curr Opin Neurol 2013;26:195-
200.
78. Zhang Y, Schmid B, Nikolaisen NK, Rasmussen MA, Aldana BI, et al. Patient iPSC-derived neurons for disease modeling of
frontotemporal dementia with mutation in CHMP2B. Stem Cell Reports 2017;8:648-58.
79. Shi Y, Kirwan P, Livesey FJ. Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. Nat
Protoc 2012;7:1836-46.