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Chu et al. J Transl Genet Genom 2023;7:66-78  https://dx.doi.org/10.20517/jtgg.2023.01  Page 64

               effective use of digital marketing and search engine optimization tools to promote the HKGI and genomic
               medicine. The allocation of resources toward genomic education and talent development in Hong Kong is a
               priority to facilitate the integration of genomic medicine into mainstream healthcare.


               Most genome projects highlighted the importance of human capacity, i.e., aptitude, knowledge, perceptions,
               responsiveness, and commitment to genomic information and campaigns. For example, the UK (a leader in
               genomic medicine development) stated that none of its success could have been realized without the
               involvement and participation of the wider UK population. As they pursue their goal to be the most
               advanced genomic healthcare ecosystem in the world in the coming decade, the UK prioritizes public
               engagement and assurance that the patient’s voice is embedded throughout decision-making, as stated in
                                                          [22]
               the Genome UK Implementation Plan 2021-2022 . Qatar Genome is also actively increasing its human
                                                                                                 [23]
               capacity by initiating several education initiatives from early school to postgraduate levels . Public
               engagement must be implemented in phases and multifactorial dimensions and platforms.

               In conclusion, with the concerted efforts of all members of the HKGI and the support of various
               stakeholders, the HKGP Pilot Phase had a smooth and successful launch. It is a long road before genomic
               medicine can become commonplace in Hong Kong and Asia. Public engagement is an ongoing and
               dynamic process. With age-specific marketing and strategic promotional plans backed by multi-disciplinary
               health reforms and long-term public education campaigns (supported by tertiary education curriculum and
               genomic knowledge outcome studies, to name but a few), we hope that via the HKGP and the related
               initiatives that geared up by its momentum, genomic literacy in Hong Kong and other Chinese-speaking
               cultures can be significantly advanced in the coming decade. Our study findings shaped the publicizing
               strategies of the Pilot Phase of the HKGP and laid a patient-oriented foundation for its Main Phase.


               DECLARATIONS
               Acknowledgments
               We would like to thank all members of the HKGI for preparing the launch of the HKGP. We thank the
               Board of Directors and the Cultural and Education Committee for their continuous support and advice. We
               also wish to acknowledge the support of the HKGP stakeholders: The Health Bureau; Hospital Authority;
               Department of Health; and Partnering Centers at The University of Hong Kong/Queen Mary Hospital, The
               Chinese University of Hong Kong/Prince of Wales Hospital, and Hong Kong Children’s Hospital.


               Authors’ contributions
               Conceptualization; project administration: Chu ATW, Chung BHY
               Data curation; formal analysis; investigation: Chu ATW, Chung CCY
               Methodology; writing-original draft: Chu ATW;
               Resources: Chu ATW, Hong Kong Genome Project, Lo SV, Chung BHY
               Supervision: Lo SV, Chung BHY
               Writing-review & editing: Chung CCY, Lo SV, Chung BHY


               Availability of data and materials
               Upon a reasonable request, Focus Group Discussion Guide, theme list, PowerPoint prompts, and focus
               group transcripts reported in this article, after de-identification, will be made available to investigators
               whose independent review committee has approved the proposed use of the data. Data will be available
               from the corresponding authors up to five years following publication.
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