Page 499 - Read Online

Page 8 of 9 Pastor et al. J Cancer Metastasis Treat 2020;6:39 I http://dx.doi.org/10.20517/2394-4722.2020.57

Consent for publication
Not applicable.

Copyright
© The Author(s) 2020.

REFERENCES
1. Nonaka T, Wong DTW. Liquid biopsy in head and neck cancer: promises and challenges. J Dent Res 2018;97:701-8.
2. Economopoulou P, Kotsantis I, Kyrodimos E, Lianidou ES, Psyrri A. Liquid biopsy: An emerging prognostic and predictive tool in head
and neck squamous cell carcinoma (HNSCC). Focus on circulating tumor cells (CTCs). Oral Oncol 2017;74:83-9.
3. Payne K, Spruce R, Beggs A, Sharma N, Kong A, et al. Circulating tumor DNA as a biomarker and liquid biopsy in head and neck
squamous cell carcinoma. Head Neck 2018;40:1598-604.
4. Ribeiro IP, de Melo JB, Carreira IM. Head and neck cancer: searching for genomic and epigenetic biomarkers in body fluids - the state of
art. Mol Cytogenet 2019;12:33.
5. Ludwig S, Sharma P, Theodoraki MN, Pietrowska M, Yerneni SS, et al. Molecular and functional profiles of exosomes from HPV(+) and
HPV(-) head and neck cancer cell lines. Front Oncol 2018;8:445.
6. Ludwig N, Yerneni SS, Razzo BM, Whiteside TL. Exosomes from HNSCC promote angiogenesis through reprogramming of endothelial
cells. Mol Cancer Res 2018;16:1798-808.
7. Muller L, Hong CS, Stolz DB, Watkins SC, Whiteside TL. Isolation of biologically-active exosomes from human plasma. J Immunol
Methods 2014;411:55-65.
8. Muller L. Exosomes: nanodust? HNO 2020;68:56-9.
9. Abels ER, Breakefield XO. Introduction to extracellular vesicles: biogenesis, RNA cargo selection, content, release, and uptake. Cell Mol
Neurobiol 2016;36:301-12.
10. Whiteside TL. Tumor-derived exosomes and their role in cancer progression. Adv Clin Chem 2016;74:103-41.
11. Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, et al. Melanoma exosomes educate bone marrow progenitor cells toward
a pro-metastatic phenotype through MET. Nat Med 2012;18:883-91.
12. Whiteside TL. The effect of tumor-derived exosomes on immune regulation and cancer immunotherapy. Future Oncol 2017;13:2583-92.
13. Franzen CA, Blackwell RH, Todorovic V, Greco KA, Foreman KA, et al. Urothelial cells undergo epithelial-to-mesenchymal transition
after exposure to muscle invasive bladder cancer exosomes. Oncogenesis 2015;4:e163.
14. Min H, Sun X, Yang X, Zhu H, Liu J, et al. Exosomes derived from irradiated esophageal carcinoma-infiltrating T cells promote
metastasis by inducing the Epithelial-Mesenchymal transition in Esophageal cancer cells. Pathol Oncol Res 2018;24:11-8.
15. Theodoraki MN, Yerneni SS, Brunner C, Theodorakis J, Hoffmann TK, et al. Plasma-derived exosomes reverse epithelial-to-
mesenchymal transition after photodynamic therapy of patients with head and neck cancer. Oncoscience2018;5:75-87.
16. Whiteside TL. Exosomes and tumor-mediated immune suppression. J Clin Invest 2016;126:1216-23.
17. Theodoraki MN, Yerneni S, Gooding WE, Ohr J, Clump DA, et al. Circulating exosomes measure responses to therapy in head and neck
cancer patients treated with cetuximab, ipilimumab, and IMRT. Oncoimmunology 2019;8:1593805.
18. Kurywchak P, Tavormina J, Kalluri R. The emerging roles of exosomes in the modulation of immune responses in cancer. Genome Med
2018;10:23.
19. Ruivo CF, Adem B, Silva M, Melo SA. The biology of cancer exosomes: insights and new perspectives. Cancer Res 2017;77:6480-8.
20. Walsh JC, Lebedev A, Aten E, Madsen K, Marciano L, et al. The clinical importance of assessing tumor hypoxia: relationship of tumor
hypoxia to prognosis and therapeutic opportunities. Antioxid Redox Signal 2014;21:1516-54.
21. Linge A, Lock S, Gudziol V, Nowak A, Lohaus F, et al. Low cancer stem cell marker expression and low hypoxia identify good prognosis
subgroups in HPV(-) HNSCC after postoperative radiochemotherapy: a multicenter study of the DKTK-ROG. Clin Cancer Res
2016;22:2639-49.
22. Kore RA, Edmondson JL, Jenkins SV, Jamshidi-Parsian A, Dings RPM, et al. Hypoxia-derived exosomes induce putative altered
pathways in biosynthesis and ion regulatory channels in glioblastoma cells. Biochem Biophys Rep 2018;14:104-13.
23. Bellassai N, D’Agata R, Jungbluth V, Spoto G. Surface plasmon resonance for biomarker detection: advances in non-invasive cancer
diagnosis. Front Chem 2019;7:570.
24. Alix-Panabieres C, Pantel K. Real-time liquid biopsy: circulating tumor cells versus circulating tumor DNA. Ann Transl Med 2013;1:18.
25. Patel KM, Tsui DW. The translational potential of circulating tumour DNA in oncology. Clin Biochem 2015;48:957-61.
26. Heitzer E, Auer M, Ulz P, Geigl JB, Speicher MR. Circulating tumor cells and DNA as liquid biopsies. Genome Med 2013;5:73.
27. Muller L, Muller-Haegele S, Mitsuhashi M, Gooding W, Okada H, et al. Exosomes isolated from plasma of glioma patients enrolled in a
vaccination trial reflect antitumor immune activity and might predict survival. Oncoimmunology 2015;4:e1008347.
28. Nolan J, Sarimollaoglu M, Nedosekin DA, Jamshidi-Parsian A, Galanzha EI, et al. In vivo flow cytometry of circulating tumor-associated
exosomes. Anal Cell Pathol (Amst) 2016;2016:1628057.
29. Halvaei S, Daryani S, Eslami SZ, Samadi T, Jafarbeik-Iravani N, et al. Exosomes in cancer liquid biopsy: a focus on breast cancer. Mol
Ther Nucleic Acids 2018;10:131-41.
30. Ludwig S, Floros T, Theodoraki MN, Hong CS, Jackson EK, et al. Suppression of lymphocyte functions by plasma exosomes correlates