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Potdar et al. Circulating tumor cells in liquid biopsies

also observed that KRT19 was not expressed down- Conflicts of interest
regulated in all breast cancer patients, possibly due to There are no conflicts of interest.
EMT of these cells during the invasive process, and
suggesting a need for aggressive treatment for these Patient consent
patients. MMP1, MMP2, and MMP9 are metastatic Patient consent was obtained from the patients.
genes involved in the invasion of tumor cells into
underlying epithelium. This is the first report that Ethics approval
[39]
liquid biopsies from all cancer patients tested express The study has been approved by ethical committee
high levels of MMP1, MMP2, and MMP9, providing guidelines of Jaslok Hospital and Research Center.
a potential new avenue for treatment of metastatic
cancers by suppression of these genes; however, these REFERENCES
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