Page 70 - Read Online
P. 70

Page 8 of 9     Rosenzweig et al. J Cancer Metastasis Treat 2022;8:46  https://dx.doi.org/10.20517/2394-4722.2022.58

                   2016;35:e205-15.  DOI  PubMed
               8.       Sertkaya A, Birkenbach A, Berlind A, Eyraud J. Examination of clinical trial costs and barriers for drug development, In: Report
                   HHSP23337007T, Department of Health and Human Services (HHS): Washington USA. 2014.
               9.       Matrisian LM, Rosenzweig A, Moravek C, Duliege AM. Trends in pancreatic cancer clinical trials in the United States. Med Res Arch
                   2021.  DOI
               10.      Woodcock J, LaVange LM. Master protocols to study multiple therapies, multiple diseases, or both. N Engl J Med 2017;377:62-70.
                   DOI  PubMed
               11.      Seligson ND, Knepper TC, Ragg S, Walko CM. Developing drugs for tissue-agnostic indications: a paradigm shift in leveraging
                   cancer biology for precision medicine. Clin Pharmacol Ther 2021;109:334-42.  DOI  PubMed  PMC
               12.      Golan T, Hammel P, Reni M, et al. Maintenance olaparib for germline BRCA-mutated metastatic pancreatic cancer. N Engl J Med
                   2019;381:317-27.  DOI  PubMed  PMC
               13.      Burris HA 3rd, Moore MJ, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for
                   patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997;15:2403-13.  DOI  PubMed
               14.      Conroy T, Desseigne F, Ychou M, et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med
                   2011;364:1817-25.  DOI  PubMed
               15.      Von Hoff DD, Ervin T, Arena FP, et al. Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. N Engl J Med
                   2013;369:1691-703.  DOI  PubMed  PMC
               16.      Wang-gillam A, Li C, Bodoky G, et al. Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer
                   after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial. Lancet 2016;387:545-57.  DOI
                   PubMed
               17.      Neoptolemos JP, Palmer DH, Ghaneh P, et al. Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in
                   patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. Lancet 2017;389:1011-24.
                   DOI  PubMed
               18.      Conroy T, Hammel P, Hebbar M, et al. FOLFIRINOX or gemcitabine as adjuvant therapy for pancreatic cancer. N Engl J Med
                   2018;379:2395-406.  DOI
               19.      Drilon A, Laetsch TW, Kummar S, et al. Efficacy of larotrectinib in TRK fusion-positive cancers in adults and children. N Engl J Med
                   2018;378:731-9.  DOI  PubMed  PMC
               20.      Doebele RC, Drilon A, Paz-ares L, et al. Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours:
                   integrated analysis of three phase 1-2 trials. Lancet Oncol 2020;21:271-82.  DOI  PubMed  PMC
               21.      Marabelle A, Fakih M, Lopez J, et al. Association of tumour mutational burden with outcomes in patients with advanced solid tumours
                   treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study. Lancet
                   Oncol 2020;21:1353-65.  DOI  PubMed
               22.      Le DT, Durham JN, Smith KN, et al. Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade. Science
                   2017;357:409-13.  DOI  PubMed  PMC
               23.      FDA  grants  accelerated  approval  to  dostarlimab-gxly  for  dMMR  advanced  solid  tumors,  2021.  Available  from:
                   https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-dostarlimab-gxly-dmmr-advanced-
                   solid-tumors [Last accessed on 13 Oct 2022].
               24.      Salama AKS, Li S, Macrae ER, et al. Dabrafenib and trametinib in patients with tumors with BRAF V600E  mutations: results of the NCI-
                   MATCH trial subprotocol H. J Clin Oncol 2020;38:3895-904.  DOI  PubMed  PMC
               25.      Hendifar A, Blais EM, Wolpin B, et al. Retrospective case series analysis of RAF family alterations in pancreatic cancer: real-world
                   outcomes from targeted and standard therapies. JCO Precis Oncol 2021;5:PO.  DOI  PubMed  PMC
               26.      Waddell N, Pajic M, Patch AM, et al. Whole genomes redefine the mutational landscape of pancreatic cancer. Nature 2015;518:495-
                   501.  DOI  PubMed  PMC
               27.      Genome Atlas Research Network. Electronic address, Cancer genome atlas research network. integrated genomic characterization of
                   pancreatic ductal adenocarcinoma. Cancer Cell 2017;32:185-203.e13.  DOI
               28.      Pishvaian MJ, Blais EM, Brody JR, et al. Overall survival in patients with pancreatic cancer receiving matched therapies following
                   molecular profiling: a retrospective analysis of the Know Your Tumor registry trial. Lancet Oncol 2020;21:508-18.  DOI  PubMed
                   PMC
               29.      Pishvaian MJ, Bender RJ, Halverson D, et al. Molecular profiling of patients with pancreatic cancer: initial results from the know your
                   tumor initiative. Clin Cancer Res 2018;24:5018-27.  DOI  PubMed
               30.      Aung KL, Fischer SE, Denroche RE, et al. Genomics-driven precision medicine for advanced pancreatic cancer: early results from the
                   COMPASS trial. Clin Cancer Res 2018;24:1344-54.  DOI  PubMed  PMC
               31.      Chan-Seng-Yue M, Kim JC, Wilson GW, et al. Transcription phenotypes of pancreatic cancer are driven by genomic events during
                   tumor evolution. Nat Genet 2020;52:231-40.  DOI
               32.      Dreyer SB, Jamieson NB, Cooke SL, et al. PRECISION-Panc: the next generation therapeutic development platform for pancreatic
                   cancer. Clin Oncol 2020;32:1-4.  DOI  PubMed
               33.      Barker AD, Sigman CC, Kelloff GJ, Hylton NM, Berry DA, Esserman LJ. I-SPY 2: an adaptive breast cancer trial design in the setting
                   of neoadjuvant chemotherapy. Clin Pharmacol Ther 2009;86:97-100.  DOI  PubMed
               34.      Alexander BM, Ba S, Berger MS, et al. Adaptive global innovative learning environment for glioblastoma: GBM AGILE. Clin Cancer
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