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RE, Klimovsky J, Lebwohl D, Jehl V, Wolin EM, Oberg K, Van   and pegylated interferon alpha-2b. J Clin Oncol 2008;26:1316-23.
                Cutsem  E, Yao  JC; RADIANT-2 Study Group. Everolimus  plus   86.  Kulke  MH,  Niedzwiecki  D,  Foster  NR,  Fruth  B,  Kunz  PL,
                octreotide  long-acting repeatable  for the  treatment  of  advanced   Kennecke HF, Wolin EM, Venook AP. Randomized phase II Study
                neuroendocrine  tumours associated  with carcinoid  syndrome   of Everolimus  versus Everolimus  plus Bevacizumab  in  patients
                (RADIANT-2): a randomised, placebo-controlled,  phase 3 study.   with locally advanced or metastatric  panxcreatic  neuroencocrine
                Lancet 2011;378:2005-12.                          tumors CALG80701 (Alliance). Proceedings of 2015 ASCO Annual
            81.  Yao  JC,  Fazio  N,  Singh  S,  Buzzoni  R, Carnaghi  C,  Wolin  E,   meeting. J Clin Oncol 2015;33:15S, abs 4005.
                Tomasek J, Raderer M, Lahner H,  Voi M, Pacaud LB, Rouyrre   87.  Mayo SC, Herman JM, Cosgrove D, Bhagat N, Kamel I, Geschwind
                N,  Sachs  C,  Valle  JW,  Fave  GD,  Van  Cutsem  E,  Tesselaar  M,   JF, Pawlik TM. Emerging approaches in the management of patients
                Shimada Y, Oh DY, Strosberg J, Kulke MH, Pavel ME; RAD001   with neuroendocrine liver  metastasis:  role of liver-directed  and
                in Advanced Neuroendocrine Tumours, Fourth Trial (RADIANT-4)   systemic therapies. J Am Coll Surg 2013;216:123-34.
                Study Group. Everolimus  for  the  treatment  of  advanced,  non-  88.  Ekeblad S, Sundin A, Janson ET, Welin S, Granberg D, Kindmark
                functional neuroendocrine tumours of the lung or gastrointestinal   H, Dunder K, Kozlovacki  G, Orlefors H, Sigurd M, Oberg K,
                tract (RADIANT-4): a randomised, placebo-controlled,  phase 3   Eriksson B, Skogseid B. Temozolomide as monotherapy is effective
                study. Lancet 2016;387:968-77.                    in treatment of advanced malignant neuroendocrine tumors. Clin
            82.  Raymond E, Dahan L Raoul JL, Bang YJ, Borbath I, Lombard-  Cancer Res 2007; 13:2986-91.
                Bohas C, Valle J, Metrakos P, Smith D, Vinik A, Chen JS, Hörsch   89.  Kouvaraki MA, Ajani JA, Hoff P, Wolff R, Evans DB, Lozano R,
                D, Hammel P, Wiedenmann B, Van Cutsem E, Patyna S, Lu DR,   Yao JC. Fluorouracil, doxorubicin, and streptozocin in the treatment
                Blanckmeister  C, Chao R, Ruszniewski P. Sunitinib  malate  for   of patients with locally advanced and metastatic  pancreatic
                the treatment of pancreatic neuroendocrine tumors. N Engl J Med   endocrine carcinomas. J Clin Oncol 2004;22:4762-71.
                2011;364:501-13.                              90.  Strosberg  JR,  Fine  RL,  Choi  J,  Nasir A,  Coppola  D,  Chen  DT,
            83.  Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM,   Helm  J,  Kvols  L.  First-line  chemotherapy  with  capecitabine  and
                Oudard S, Negrier S, Szczylik C, Pili R, Bjarnason GA, Garcia-  temozolomide  in patients  with metastatic  pancreatic  endocrine
                del-Muro X, Sosman JA, Solska E, Wilding G, Thompson JA, Kim   carcinomas. Cancer 2011;117:268-75.
                ST,  Chen  I,  Huang  X,  Figlin  RA.  Overall  survival  and  updated   91.  Berruti A, Fazio N, Ferrero A, Brizzi MP, Volante M, Nobili E, Tozzi
                results for sunitinib compared with interferon alfa in patients with   L, Bodei L, Torta M, D’Avolio A, Priola AM, Birocco N, Amoroso
                metastatic renal cell carcinoma. J Clin Oncol 2009;27:3584-90.  V, Biasco G, Papotti M, Dogliotti L. Bevacizumab plus octreotide
            84.  Oxboel J,  Binderup  T, Knigge U,  Kjaer  A.  Quantitative  gene-  and metronomic capecitabine in patients with metastatic well-to-
                expression of the tumor angiogenesis markers vascular endothelial   moderately  differentiated  neuroendocrine tumors: the xelbevoct
                growth factor, integrin alphaV and integrin beta3 in human   study. BMC Cancer 2014;14:184.
                neuroendocrine tumors. Oncol Rep 2009;21:769-75.  92.  Walter T, Bruneton D, Cassier PA, Hervieu V, Pilleul F, Scoazec JY,
            85.  Yao JC, Phan A, Hoff PM, Chen HX, Charnsangavej C,  Yeung   Chayvialle JA, Lombard-Bohas C. Evaluation of the combination
                SC, Hess K, Ng C, Abbruzzese JL, Ajani JA. Targeting vascular   5-fluorouracil, dacarbazine, and epirubicin in patients with advanced
                endothelial growth factor in advanced carcinoid tumor: a random   well-differentiated neuroendocrine tumors. Clin Colorectal Cancer
                assignment  phase II study of depot  octreotide  with bevacizumab   2010;9:248-54.









































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