Page 84 - Read Online

Shuber A. Improved fecal DNA test for colorectal cancer correlates with loss of p16 expression that results in
screening. Clin Gastroenterol Hepatol 2007;5:111-7. poorer prognosis in esophageal squamous cell carcinomas.
81. Kamimae S, Yamamoto E, Yamano HO, Nojima M, Suzuki H, Dis Esophagus 2008;21:125-31.
Ashida M, Hatahira T, Sato A, Kimura T, Yoshikawa K, 95. Sung CO, Han SY, Kim SH. Low expression of claudin-4 is
Harada T, Hayashi S, Takamaru H, Maruyama R, Kai M, associated with poor prognosis in esophageal squamous cell
Nishiwaki M, Sugai T, Sasaki Y, Tokino T, Shinomura Y, carcinoma. Ann Surg Oncol 2011;18:273-81.
Imai K, Toyota M. Epigenetic alteration of DNA in mucosal 96. Mori M, Mimori K, Shiraishi T, Alder H, Inoue H, Tanaka Y,
wash fl uid predicts invasiveness of colorectal tumors. Sugimachi K, Huebner K, Croce CM. Altered expression
Cancer Prev Res (Phila) 2011;4:674-83. of Fhit in carcinoma and precarcinomatous lesions of the
82. Kane MF, Loda M, Gaida GM, Lipman J, Mishra R, esophagus. Cancer Res 2000;60:1177-82.
Goldman H, Jessup JM, Kolodner R. Methylation of the 97. Xue HC, Wang JM, Xu B, Guo GP, Hua ZL, Zhou Q, Zhu ZH,
hMLH1 promoter correlates with lack of expression of hMLH1 Ma ZK, Gao J. Correlation of aberrant methylation of MGMT
in sporadic colon tumors and mismatch repair-defective human gene to MTHFR C677T genetic polymorphisms in esophageal
tumor cell lines. Cancer Res 1997;57:808-11. squamous cell carcinoma. Ai Zheng 2008;27:1256-62.
83. Veigl ML, Kasturi L, Olechnowicz J, Ma AH, Lutterbaugh JD, 98. Ling ZQ, Li P, Ge MH, Hu FJ, Fang XH, Dong ZM,
Periyasamy S, Li GM, Drummond J, Modrich PL, Mao WM. Aberrant methylation of different DNA repair genes
Sedwick WD, Markowitz SD. Biallelic inactivation of demonstrates distinct prognostic value for esophageal cancer.
hMLH1 by epigenetic gene silencing, a novel mechanism Dig Dis Sci 2011;56:2992-3004.
causing human MSI cancers. Proc Natl Acad Sci U S A 99. Schulmann K, Sterian A, Berki A, Yin J, Sato F, Xu Y,
1998;95:8698-702. Olaru A, Wang S, Mori Y, Deacu E, Hamilton J, Kan T,
84. Shin SK, Nagasaka T, Jung BH, Matsubara N, Kim WH, Krasna MJ, Beer DG, Pepe MS, Abraham JM, Feng Z,
Carethers JM, Boland CR, Goel A. Epigenetic and genetic Schmiegel W, Greenwald BD, Meltzer SJ. Inactivation of
alterations in Netrin-1 receptors UNC5C and DCC in human p16, RUNX3, and HPP1 occurs early in Barrett’s-associated
colon cancer. Gastroenterology 2007;133:1849-57. neoplastic progression and predicts progression risk. Oncogene
85. Hibi K, Mizukami H, Shirahata A, Goto T, Sakata M, 2005;24:4138-48.
Sanada Y. Aberrant methylation of the netrin-1 receptor genes 100. Yao D, Shi J, Shi B, Wang N, Liu W, Zhang G, Ji M, Xu L,
UNC5C and DCC detected in advanced colorectal cancer. He N, Hou P. Quantitative assessment of gene methylation
World J Surg 2009;33:1053-7. and their impact on clinical outcome in gastric cancer.
86. Tanaka M, Chang P, Li Y, Li D, Overman M, Maru DM, Clin Chim Acta 2012;413:787-94.
Sethi S, Phillips J, Bland GL, Abbruzzese JL, Eng C. 101. Murai M, Toyota M, Suzuki H, Satoh A, Sasaki Y, Akino K,
Association of CHFR promoter methylation with disease Ueno M, Takahashi F, Kusano M, Mita H, Yanagihara K,
recurrence in locally advanced colon cancer. Clin Cancer Res Endo T, Hinoda Y, Tokino T, Imai K. Aberrant methylation
2011;17:4531-40. and silencing of the BNIP3 gene in colorectal and gastric
87. Yi JM, Dhir M, Van Neste L, Downing SR, Jeschke J, cancer. Clin Cancer Res 2005;11:1021-7.
Glockner SC, de Freitas Calmon M, Hooker CM, Funes JM, 102. Yuasa Y, Nagasaki H, Akiyama Y, Hashimoto Y, Takizawa T,
Boshoff C, Smits KM, van Engeland M, Weijenberg MP, Kojima K, Kawano T, Sugihara K, Imai K, Nakachi K. DNA
Iacobuzio-Donahue CA, Herman JG, Schuebel KE, Baylin SB, methylation status is inversely correlated with green tea intake
Ahuja N. Genomic and epigenomic integration identifi es and physical activity in gastric cancer patients. Int J Cancer
a prognostic signature in colon cancer. Clin Cancer Res 2009;124:2677-82.
2011;17:1535-45. 103. Ben Ayed-Guerfali D, Benhaj K, Khabir A, Abid M,
88. Baba Y, Nosho K, Shima K, Huttenhower C, Tanaka N, Bayrouti MI, Sellami-Boudawara T, Gargouri A,
Hazra A, Giovannucci EL, Fuchs CS, Ogino S. Mokdad-Gargouri R. Hypermethylation of tumor-related
Hypomethylation of the IGF2 DMR in colorectal tumors, genes in Tunisian patients with gastric carcinoma: clinical and
detected by bisulfi te pyrosequencing, is associated with poor biological signifi cance. J Surg Oncol 2011;103:687-94.
prognosis. Gastroenterology 2010;139:1855-64. 104. Shi J, Zhang G, Yao D, Liu W, Wang N, Ji M, He N, Shi B,
89. Wong JJ, Hawkins NJ, Ward RL. Colorectal cancer: a model Hou P. Prognostic signifi cance of aberrant gene methylation in
for epigenetic tumorigenesis. Gut 2007;56:140-8. gastric cancer. Am J Cancer Res 2012;2:116-29.
90. Ji W, Hernandez R, Zhang XY, Qu GZ, Frady A, Varela M, 105. Jee CD, Kim MA, Jung EJ, Kim J, Kim WH. Identifi cation of
Ehrlich M. DNA demethylation and pericentromeric genes epigenetically silenced by CpG methylation in human
rearrangements of chromosome 1. Mutat Res 1997;379:33-41. gastric carcinoma. Eur J Cancer 2009;45:1282-93.
91. Suter CM, Martin DI, Ward RL. Hypomethylation of L1 106. Peng DF, Hu TL, Schneider BG, Chen Z, Xu ZK, El-Rifai W.
retrotransposons in colorectal cancer and adjacent normal Silencing of glutathione peroxidase 3 through DNA
tissue. Int J Colorectal Dis 2004;19:95-101. hypermethylation is associated with lymph node metastasis in
92. Ogino S, Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, gastric carcinomas. PLoS One 2012;7:e46214.
Kirkner GJ, Fuchs CS. LINE-1 hypomethylation is inversely 107. Kongkham PN, Northcott PA, Ra YS, Nakahara Y,
associated with microsatellite instability and CpG island Mainprize TG, Croul SE, Smith CA, Taylor MD, Rutka JT. An
methylator phenotype in colorectal cancer. Int J Cancer epigenetic genome-wide screen identifi es SPINT2 as a novel
2008;122:2767-73. tumor suppressor gene in pediatric medulloblastoma. Cancer
93. Estecio MR, Gharibyan V, Shen L, Ibrahim AE, Doshi K, Res 2008;68:9945-53.
He R, Jelinek J, Yang AS, Yan PS, Huang TH, Tajara EH, 108. Wang L, Chen S, Xue M, Zhong J, Wang X, Gan L, Lam EK,
Issa JP. LINE-1 hypomethylation in cancer is highly variable Liu X, Zhang J, Zhou T, Yu J, Jin H, Si J. Homeobox D10
and inversely correlated with microsatellite instability. PLoS gene, a candidate tumor suppressor, is downregulated through
One 2007;2:e399. promoter hypermethylation and associated with gastric
94. Fujiwara S, Noguchi T, Takeno S, Kimura Y, Fumoto S, carcinogenesis. Mol Med 2012;18:389-400.
Kawahara K. Hypermethylation of p16 gene promoter 109. Hibi K, Sakata M, Yokomizo K, Kitamura YH, Sakuraba K,

Journal of Cancer Metastasis and Treatment ¦ Volume 1 ¦ Issue 3 ¦ October 15, 2015 ¦ 121