Page 79 - Read Online
P. 79

Page 22 of 25        Lue et al. J Cancer Metastasis Treat 2022;8:11  https://dx.doi.org/10.20517/2394-4722.2021.193

               81.       Fontan L, Hatcher J, Scott D, et al. Chemically induced degradation of malt1 to treat B-cell lymphomas. Blood 2019;134:2073.  DOI
               82.       Hatcher JM, Du G, Fontán L, et al. Peptide-based covalent inhibitors of MALT1 paracaspase. Bioorg Med Chem Lett 2019;29:1336-
                    9.  DOI  PubMed
               83.       Quancard J, Klein T, Fung SY, et al. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient
                    patient. Nat Chem Biol 2019;15:304-13.  DOI
               84.       Lu T, Connolly PJ, Philippar U, et al. Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1
                    protease. Bioorg Med Chem Lett 2019;29:126743.  DOI  PubMed
               85.       Fontán L, Qiao Q, Hatcher JM, et al. Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth. J Clin
                    Invest 2018;128:4397-412.  DOI  PubMed  PMC
               86.       first-in-class MALT1 blocker deal. Nat Biotechnol 2019;37:112.  DOI  PubMed
               87.       Xia M, David L, Teater M, et al. BCL10 gain-of-function mutations aberrantly induce canonical and non-canonical NF-Kb activation
                    and resistance to IBRUTINIB in ABC-DLBCL. Blood 2020;136:2-3.  DOI
               88.       Philippar U, Lu T, Vloemans N, et al. Abstract 5690: discovery of JNJ-67856633: a novel, first-in-class MALT1 protease inhibitor
                    for the treatment of B cell lymphomas. Cancer research 2020;80:5690.  DOI
               89.       Kiyasu J, Miyoshi H, Hirata A, et al. Expression of programmed cell death ligand 1 is associated with poor overall survival in patients
                    with diffuse large B-cell lymphoma. Blood 2015;126:2193-201.  DOI  PubMed  PMC
               90.       Godfrey J, Tumuluru S, Bao R, et al.  DOI  PubMed  PMC
               91.       Ansell SM, Minnema MC, Johnson P, et al. Nivolumab for relapsed/refractory diffuse large B-Cell lymphoma in patients ineligible
                    for or having failed autologous transplantation: a single-arm, phase II study. J Clin Oncol 2019;37:481-9.  DOI  PubMed  PMC
               92.       Smith SD, Till BG, Shadman MS, et al. Pembrolizumab with R-CHOP in previously untreated diffuse large B-cell lymphoma:
                    potential for biomarker driven therapy. Br J Haematol 2020;189:1119-26.  DOI  PubMed
                                                                                                  2
               93.       Nowakowski GS, Willenbacher W, Greil R, et al. Safety and efficacy of PD-L1 inhibitor durvalumab with R-CHOP or R   -CHOP in
                    subjects with previously untreated, high-risk DLBCL. JCO 2019;37:7520-7520.  DOI
               94.       Nowakowski GS, Kalakonda N, Truemper L, et al; And the MEDI4736-DLBCL-001 Trial Investigators. Phase II study of
                    durvalumab (anti-PD-L1 antibody) in combination with R-CHOP or lenalidomide plus R-CHOP in previously untreated, high-risk
                    diffuse large B-cell lymphoma. JCO 2017;35:TPS7573-TPS7573.  DOI
               95.       Hawkes EA, Manos K, Smith C, et al. AvR-CHOP: feasibility study of induction and maintenance AVELUMAB plus R-CHOP in
                    patients with diffuse large B-Cell lymphoma (DLBCL). Blood 2019;134:5332.  DOI
               96.       Klapper W, Stoecklein H, Zeynalova S, et al; German High-Grade Non-Hodgkin's Lymphoma Study Group. Structural aberrations
                    affecting the MYC locus indicate a poor prognosis independent of clinical risk factors in diffuse large B-cell lymphomas treated
                    within randomized trials of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL). Leukemia 2008;22:2226-9.
                    DOI  PubMed
               97.       Valera A, López-Guillermo A, Cardesa-Salzmann T, et al; Grup per l’Estudi dels Limfomes de Catalunya i Balears (GELCAB).
                    MYC protein expression and genetic alterations have prognostic impact in patients with diffuse large B-cell lymphoma treated with
                    immunochemotherapy. Haematologica 2013;98:1554-62.  DOI  PubMed  PMC
               98.       Horn H, Ziepert M, Becher C, et al; German High-Grade Non-Hodgkin Lymphoma Study Group. MYC status in concert with BCL2
                    and BCL6 expression predicts outcome in diffuse large B-cell lymphoma. Blood 2013;121:2253-63.  DOI  PubMed
               99.       Barrans S, Crouch S, Smith A, et al. Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell
                    lymphoma treated in the era of rituximab. J Clin Oncol 2010;28:3360-5.  DOI  PubMed
               100.      Oki Y, Noorani M, Lin P, et al. Double hit lymphoma: the MD Anderson Cancer Center clinical experience. Br J Haematol
                    2014;166:891-901.  DOI  PubMed
               101.      Petrich AM, Gandhi M, Jovanovic B, et al. Impact of induction regimen and stem cell transplantation on outcomes in double-hit
                    lymphoma: a multicenter retrospective analysis. Blood 2014;124:2354-61.  DOI  PubMed
               102.      Wang  W,  Hu  S,  Lu  X,  Young  KH,  Medeiros  LJ.  Triple-hit  B-cell  Lymphoma  with  MYC,  BCL2,  and  BCL6
                    translocations/rearrangements: clinicopathologic features of 11 cases. Am J Surg Pathol 2015;39:1132-9.  DOI  PubMed
               103.      Hu S, Xu-Monette ZY, Tzankov A, et al. MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell
                    subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International
                    DLBCL Rituximab-CHOP Consortium Program. Blood 2013;121:4021-31; quiz 4250.  DOI  PubMed  PMC
               104.      Morin RD, Johnson NA, Severson TM, et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell
                    lymphomas of germinal-center origin. Nat Genet 2010;42:181-5.  DOI  PubMed  PMC
               105.      Bödör C, O'Riain C, Wrench D, et al. EZH2 Y641 mutations in follicular lymphoma. Leukemia 2011;25:726-9.  DOI  PubMed
               106.      Zhang X, Zhao X, Fiskus W, et al. Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of
                    histone modification in aggressive B-Cell lymphomas. Cancer Cell 2012;22:506-23.  DOI  PubMed  PMC
               107.      Yan J, Ng SB, Tay JL, et al. EZH2 overexpression in natural killer/T-cell lymphoma confers growth advantage independently of
                    histone methyltransferase activity. Blood 2013;121:4512-20.  DOI  PubMed
               108.      Arisan S, Buyuktuncer ED, Palavan-Unsal N, Caşkurlu T, Cakir OO, Ergenekon E. Increased expression of EZH2, a polycomb group
                    protein, in bladder carcinoma. Urol Int 2005;75:252-7.  DOI  PubMed
               109.      Velichutina I, Shaknovich R, Geng H, et al. EZH2-mediated epigenetic silencing in germinal center B cells contributes to
                    proliferation and lymphomagenesis. Blood 2010;116:5247-55.  DOI  PubMed  PMC
   74   75   76   77   78   79   80   81   82   83   84