Page 70 - Read Online
P. 70
Page 32 of 36 Dave et al. J Cancer Metastasis Treat 2020;6:46 I http://dx.doi.org/10.20517/2394-4722.2020.106
transformation in JB6 mouse epidermal cells. Proc Natl Acad Sci U S A 1994;91:609-13.
142. Huang C, Ma WY, Young MR, Colburn N, Dong Z. Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1
transactivation and transformation in mouse JB6 cells. Proc Natl Acad Sci U S A 1998;95:156-61.
143. Chinery R, Beauchamp RD, Shyr Y, Kirkland SC, Coffey RJ, Morrow JD. Antioxidants reduce cyclooxygenase-2 expression,
prostaglandin production, and proliferation in colorectal cancer cells. Cancer Res 1998;58:2323-7.
144. Hou DX, Fujii M, Terahara N, Yoshimoto M. Molecular Mechanisms behind the chemopreventive effects of anthocyanidins. J Biomed
Biotechnol 2004;2004:321-5.
145. Hou DX, Ose T, Lin S, et al. Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: structure-activity relationship and
mechanisms involved. Int J Oncol 2003;23:705-12.
146. Li D, Zhang Y, Liu Y, Sun R, Xia M. Purified anthocyanin supplementation reduces dyslipidemia, enhances antioxidant capacity, and
prevents insulin resistance in diabetic patients. J Nutr 2015;145:742-8.
147. Shih PH, Yeh CT, Yen GC. Anthocyanins induce the activation of phase II enzymes through the antioxidant response element pathway
against oxidative stress-induced apoptosis. J Agric Food Chem 2007;55:9427-35.
148. Yi L, Chen CY, Jin X, et al. Structural requirements of anthocyanins in relation to inhibition of endothelial injury induced by oxidized
low-density lipoprotein and correlation with radical scavenging activity. FEBS Lett 2010;584:583-90.
149. Esposito D, Chen A, Grace MH, Komarnytsky S, Lila MA. Inhibitory effects of wild blueberry anthocyanins and other flavonoids on
biomarkers of acute and chronic inflammation in vitro. J Agric Food Chem 2014;62:7022-8.
150. Peiffer DS, Zimmerman NP, Wang LS, et al. Chemoprevention of esophageal cancer with black raspberries, their component
anthocyanins, and a major anthocyanin metabolite, protocatechuic acid. Cancer Prev Res (Phila) 2014;7:574-84.
151. Charepalli V, Reddivari L, Radhakrishnan S, Vadde R, Agarwal R, Vanamala JK. Anthocyanin-containing purple-fleshed potatoes
suppress colon tumorigenesis via elimination of colon cancer stem cells. J Nutr Biochem 2015;26:1641-9.
152. Fimognari C, Berti F, Nüsse M, Cantelli-Forti G, Hrelia P. Induction of apoptosis in two human leukemia cell lines as well as
differentiation in human promyelocytic cells by cyanidin-3-O-beta-glucopyranoside. Biochem Pharmacol 2004;67:2047-56.
153. Chang YC, Huang HP, Hsu JD, Yang SF, Wang CJ. Hibiscus anthocyanins rich extract-induced apoptotic cell death in human
promyelocytic leukemia cells. Toxicol Appl Pharmacol 2005;205:201-12.
154. Oak MH, Bedoui JE, Madeira SV, Chalupsky K, Schini-Kerth VB. Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in
vascular smooth muscle cells by preventing activation of p38 MAPK and JNK. Br J Pharmacol 2006;149:283-90.
155. Breinholt VM, Offord EA, Brouwer C, Nielsen SE, Brøsen K, Friedberg T. In vitro investigation of cytochrome P450-mediated
metabolism of dietary flavonoids. Food Chem Toxicol 2002;40:609-16.
156. Mazza G, Kay CD, Cottrell T, Holub BJ. Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J
Agric Food Chem 2002;50:7731-7.
157. Kay CD, Mazza GJ, Holub BJ. Anthocyanins exist in the circulation primarily as metabolites in adult men. J Nutr 2005;135:2582-8.
158. Shimoi K, Okada H, Furugori M, et al. Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans. FEBS Lett
1998;438:220-4.
159. Donovan JL, Crespy V, Manach C, et al. Catechin is metabolized by both the small intestine and liver of rats. J Nutr 2001;131:1753-7.
160. Spencer JP, Chowrimootoo G, Choudhury R, Debnam ES, Srai SK, Rice-Evans C. The small intestine can both absorb and glucuronidate
luminal flavonoids. FEBS Lett 1999;458:224-30.
161. Oliveira EJ, Watson DG, Grant MH. Metabolism of quercetin and kaempferol by rat hepatocytes and the identification of flavonoid
glycosides in human plasma. Xenobiotica 2002;32:279-87.
162. Kuhnle G, Spencer JP, Schroeter H, et al. Epicatechin and catechin are O-methylated and glucuronidated in the small intestine. Biochem
Biophys Res Commun 2000;277:507-12.
163. Mojarrabi B, Mackenzie PI. Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon.
Biochem Biophys Res Commun 1998;247:704-9.
164. Strassburg CP, Nguyen N, Manns MP, Tukey RH. Polymorphic expression of the UDP-glucuronosyltransferase UGT1A gene locus in
human gastric epithelium. Mol Pharmacol 1998;54:647-54.
165. Cheng Z, Radominska-Pandya A, Tephly TR. Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8
and 1A10. Drug Metab Dispos 1999;27:1165-70.
166. Crespy V, Morand C, Manach C, Besson C, Demigne C, Remesy C. Part of quercetin absorbed in the small intestine is conjugated and
further secreted in the intestinal lumen. Am J Physiol 1999;277:G120-6.
167. Piskula MK, Terao J. Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation
enzymes in rat tissues. J Nutr 1998;128:1172-8.
168. Manach C, Morand C, Crespy V, et al. Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant
properties. FEBS Lett 1998;426:331-6.
169. Coughtrie MW, Sharp S, Maxwell K, Innes NP. Biology and function of the reversible sulfation pathway catalysed by human
sulfotransferases and sulfatases. Chem Biol Interact 1998;109:3-27.
170. Del Rio D, Borges G, Crozier A. Berry flavonoids and phenolics: bioavailability and evidence of protective effects. Br J Nutr 2010;104
Suppl 3:S67-90.
171. Grynkiewicz G, Ślifirski P. Curcumin and curcuminoids in quest for medicinal status. Acta Biochimica Polonica 2012;59:201-12.
172. Kocaadam B, Şanlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health. Crit Rev Food Sci Nutr
2017;57:2889-95.